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挪威国内隐孢子虫和贾第虫感染是否诊断不足?

[Are domestic Cryptosporidium and Giardia infections in Norway underdiagnosed?].

作者信息

Nygård Karin, Vold Line, Robertson Lucy, Lassen Jørgen

机构信息

Division for smittevern, Nasjonalt forkehelseinstitutt, Oslo.

出版信息

Tidsskr Nor Laegeforen. 2003 Dec 4;123(23):3406-9.

Abstract

BACKGROUND

Cryptosporidium and Giardia are recognised as common causes of waterborne disease in several countries. In order to describe investigative practices for these protozoan parasites in Norway, we surveyed medical microbiology laboratories nationwide for faecal screening policies and methods used for detection of Cryptosporidium and Giardia.

MATERIAL AND METHODS

All medical microbiology laboratories in Norway received questionnaires on laboratory methods, indications for screening, and numbers of samples investigated over the 1998-2002 period.

RESULTS

Of the 22 laboratories that receive faecal samples, 17 had established diagnostic routines for Giardia detection, 14 for Cryptosporidium. Examination for Giardia cysts was standard procedure in all 17 laboratories, mainly in specimens from immigrants and travellers returning from abroad. Examination for Cryptosporidium was, on the other hand, infrequent. Ten of the 14 laboratories reported less than 10 examinations per year. Giardia was frequently detected, with 1 to 6% positive samples in the various laboratories. Cryptosporidium was seldom detected; all laboratories reported only 0-1 positive sample per year.

INTERPRETATION

While laboratories frequently screen faecal samples for Giardia, screening for Cryptosporidium is rare. Little is known about the public health significance of domestic infections with these parasites in Norway; further investigation is needed in order to estimate the burden of disease they cause and to implement control measures if required.

摘要

背景

隐孢子虫和贾第虫被公认为是多个国家水源性疾病的常见病因。为了描述挪威针对这些原生动物寄生虫的检测方法,我们对全国的医学微生物实验室进行了调查,了解其用于检测隐孢子虫和贾第虫的粪便筛查政策和方法。

材料与方法

向挪威所有医学微生物实验室发放了问卷,内容涉及1998 - 2002年期间的实验室检测方法、筛查指征以及检测样本数量。

结果

在接收粪便样本的22个实验室中,17个已建立了检测贾第虫的诊断程序,14个已建立了检测隐孢子虫的诊断程序。所有17个实验室检测贾第虫包囊均为标准程序,主要针对来自国外的移民和旅行者的样本。另一方面,检测隐孢子虫的情况较少。14个实验室中有10个报告每年检测次数少于10次。贾第虫经常被检测到,各实验室阳性样本率为1%至6%。隐孢子虫很少被检测到;所有实验室报告每年仅有0 - 1个阳性样本。

解读

虽然实验室经常对粪便样本进行贾第虫筛查,但对隐孢子虫的筛查却很少见。对于挪威国内这些寄生虫感染的公共卫生意义知之甚少;需要进一步调查以评估它们所导致的疾病负担,并在必要时实施控制措施。

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