Tawana Mpho, Onyiche ThankGod E, Ramatla Tsepo, Nkhebenyane Sebolelo Jane, Grab Dennis J, Thekisoe Oriel
Unit for Environmental Sciences and Management, North-West University, Potchefstroom 2531, South Africa.
Department of Zoology and Entomology, University of the Free State, Phuthaditjhaba 9866, South Africa.
Microorganisms. 2024 Nov 25;12(12):2426. doi: 10.3390/microorganisms12122426.
This study presents a systematic review and meta-analysis approach of species prevalence studies in animal and human hosts published between 1980 and 2020 in South Africa. Extensive searches were conducted on three electronic databases including PubMed, ScienceDirect and Google Scholar. The findings indicated an overall pooled prevalence estimate (PPE) of spp. infections in animals and humans at 21.5% and 18.1%, respectively. The PCR-RFLP appeared to be the most sensitive diagnostic method with a PPE of 77.8% for the detection of spp. infections followed by ELISA (66.7%); LAMP (45.4%); PCR (25.3%); qPCR (20.7%); microscopy (10.1%); IFAT (8.4%); and RDT (7.9%). In animal hosts, had the highest PPE of 3.7%, followed by (1.5%), (1.4%) and (1.0%), while in humans, also had the highest PPE of 18.3% followed by at 0.4%. The data generated in this study indicated that spp. infections were highly prevalent in both animals and humans in South Africa, especially in the KwaZulu-Natal and North West provinces. However, we further observed that there was a lack of prevalence studies for both animals and humans in some of the provinces. This study highlights the necessity for a "One Health" strategic approach promoting public hygiene, animal husbandry and regular screening for spp. infections in both animals and humans.
本研究对1980年至2020年期间在南非发表的关于动物和人类宿主物种流行率研究进行了系统综述和荟萃分析。在包括PubMed、ScienceDirect和谷歌学术在内的三个电子数据库中进行了广泛检索。研究结果表明，动物和人类中 spp. 感染的总体合并流行率估计（PPE）分别为21.5%和18.1%。PCR-RFLP似乎是最敏感的诊断方法，检测 spp. 感染的PPE为77.8%，其次是ELISA（66.7%）；LAMP（45.4%）；PCR（25.3%）；qPCR（20.7%）；显微镜检查（10.1%）；间接荧光抗体试验（8.4%）；以及快速诊断试验（7.9%）。在动物宿主中， 的PPE最高，为3.7%，其次是 （1.5%）、 （1.4%）和 （1.0%），而在人类中， 的PPE也最高，为18.3%，其次是 ，为0.4%。本研究生成的数据表明，spp. 感染在南非的动物和人类中都非常普遍，尤其是在夸祖鲁-纳塔尔省和西北省。然而，我们进一步观察到，一些省份缺乏针对动物和人类的流行率研究。本研究强调了采取“同一健康”战略方法促进公共卫生、畜牧业以及对动物和人类进行spp. 感染定期筛查必要性。
