Trace Element Centre, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
J Trace Elem Med Biol. 2011 Jan;25 Suppl 1:S17-21. doi: 10.1016/j.jtemb.2010.11.001. Epub 2010 Dec 8.
Assessing the quality of measurements is of interest to organizers of external quality assessment schemes (EQAS, or proficiency testing schemes), laboratory analysts and managers, users of laboratory results and other agencies. Scheme organizers run test programmes, define standards of acceptable and non-acceptable performance, and interact with participants and oversight authorities. Laboratory personnel are responsible for the quality management system and to choose whether to accept the standards set by scheme organizers or to adopt their own. Users receive and act upon the laboratory results. Schemes within the same analytical sector are often organized very differently causing contradictory assessment of performance. The Network of EQAS in occupational and environmental laboratory medicine established collaborative projects designed to enhance assessment of measurement quality and to improve the reliability of laboratory results. To address the issue of variations in assessing the quality of measurements, and in response to comments from some participants, standards derived from biological variation, rather than on the analytical performance of participants have been developed. Evaluation of test materials with respect to homogeneity and stability, and work on methods to give the assigned value to test materials, has also been undertaken. Following from these projects, further collaboration is planned which will provide better quality assessment of measurement to scheme participants and their users.
评估测量质量引起了外部质量评估计划(EQAS,或能力验证计划)的组织者、实验室分析人员和管理人员、实验室结果的使用者以及其他机构的关注。计划组织者运行测试计划,定义可接受和不可接受性能的标准,并与参与者和监督机构进行互动。实验室人员负责质量管理体系,并决定是接受计划组织者设定的标准,还是采用自己的标准。用户接收并根据实验室结果采取行动。同一分析领域内的计划通常组织方式非常不同,导致对性能的评估相互矛盾。职业和环境实验室医学中的 EQAS 网络建立了协作项目,旨在提高测量质量评估,并提高实验室结果的可靠性。为了解决评估测量质量的变化问题,并回应一些参与者的意见,已经制定了基于生物学变异而不是参与者分析性能的标准。还对测试材料的均匀性和稳定性进行了评估,并开展了为测试材料赋值的方法的工作。在此基础上,计划进一步开展合作,为计划参与者及其用户提供更好的测量质量评估。