Department of Stomatology, The First Hospital of Wuhan, Wuhan, China.
J Endod. 2011 Jan;37(1):80-4. doi: 10.1016/j.joen.2010.10.004.
This study examined the ability of two versions of QMix, an experimental antimicrobial irrigant, on removal of canal wall smear layers and debris using an open canal design.
Cleaned and shaped single-rooted human root canals were irrigated with NaOCl as the initial irrigant and one of the following as the final irrigant: (1) QMix I (pH = 8), (2) QMix II (pH = 7.5), (3) distilled water, (4) 17% EDTA, and (5) BioPure MTAD (Dentsply Tulsa Dental Specialties, Tulsa, OK). Smear and debris scores were evaluated in the coronal, middle, and apical thirds of longitudinally fractured canal spaces using scanning electron microscopy and analyzed using Cochran-Mantel-Haenszel statistic.
Smear scores, when the overall canal was considered, differences were observed among groups except groups 1 versus 4 and groups 2 versus 4. After adjusting for canal levels, all groups differed significantly from each other (p < 0.005) with the exception of groups 2 versus 5. For the debris scores, no significant difference was observed among the treatment groups when the overall canal was considered and after adjusting for the effect of canal level.
Within the limitations of an open-canal design, the two experimental QMix versions are as effective as 17% EDTA in removing canal wall smear layers after the use of 5.25% NaOCl as the initial rinse.
本研究采用开放式根管设计,考察了两种 QMix(一种实验性抗菌冲洗剂)制剂去除根管壁玷污层和碎屑的能力。
用 5.25%次氯酸钠作为初始冲洗液,对清洁和成形的单根人牙根进行冲洗,然后用以下溶液之一作为终末冲洗液:(1)QMix I(pH=8)、(2)QMix II(pH=7.5)、(3)蒸馏水、(4)17%EDTA 和(5)BioPure MTAD(登士柏塔尔萨齿科有限公司,塔尔萨,俄克拉荷马州)。采用扫描电子显微镜观察根管冠、中、根尖三分之一的玷污层和碎屑评分,并采用 Cochran-Mantel-Haenszel 统计进行分析。
当考虑整个根管时,除了第 1 组与第 4 组和第 2 组与第 4 组之间没有差异外,其他各组的玷污层评分差异均有统计学意义。调整根管水平后,各组之间均有显著差异(p<0.005),但第 2 组与第 5 组之间除外。对于碎屑评分,当考虑整个根管时,各治疗组之间没有显著差异,且在调整根管水平的影响后也是如此。
在开放式根管设计的限制内,两种实验性 QMix 版本在使用 5.25%次氯酸钠作为初始冲洗液后,去除根管壁玷污层的效果与 17%EDTA 相同。