Röckelein G, Ulmer R, Schwille R
Institute of Pathology, University of Erlangen-Nürnberg, Federal Republic of Germany.
Virchows Arch A Pathol Anat Histopathol. 1990;417(2):151-8. doi: 10.1007/BF02190533.
The placental villi of 61 early abortions with known karyotype and 7 legally induced abortions were investigated by scanning electron microscopy and documented in standardised enlargements. Five groups were established from the findings: uniformly branched villi with a velvety surface (group A) were found in 4 of the 7 induced abortions, abundant syncytial sprouts (group B) in 4 of the 6 cases with monosomy X; all 5 cases of triploidy were classified in the group bulbous or spherical villi (group C); 13 out of 25 cases of trisomy were found to have little branching and a surface densely covered with microvilli (group D), while 14 out of the 25 cases of euploidy belonged in the group with slender villi and surface with focal areas of denudation (group E). Forty of the 68 cases were properly assignable to the correct groups (58.8%). The non-uniformity of the villous morphology in the case of induced abortions shows that there is no uniform development of the (early) placenta. The variable morphology seen in abortions with euploidy reflects the various mechanisms of abortion applicable to this group.
对61例已知核型的早期流产胎盘绒毛和7例合法引产胎盘绒毛进行了扫描电子显微镜检查，并以标准化放大倍数记录。根据检查结果分为五组：在7例引产中有4例发现表面呈天鹅绒状的均匀分支绒毛（A组）；6例X单体中有4例出现丰富的合体滋养层芽（B组）；所有5例三倍体均归类为球状或球形绒毛组（C组）；25例三体中有13例分支少且表面密布微绒毛（D组），而25例整倍体中有14例属于绒毛细长且表面有局灶性剥脱区的组（E组）。68例中有40例可正确归入相应组（58.8%）。引产时绒毛形态的不一致表明（早期）胎盘没有统一的发育过程。整倍体流产中所见的形态变化反映了适用于该组的各种流产机制。
