产前磁共振成像在 Dandy-Walker 综合征中的应用：正中矢状位面积分析。

Prenatal MR imaging of Dandy-Walker complex: midline sagittal area analysis.

机构信息

Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital and Chang Gung University, Kwei-Shan, Tao Yuan, Taiwan, ROC.

出版信息

Eur J Radiol. 2012 Jan;81(1):e26-30. doi: 10.1016/j.ejrad.2010.11.003. Epub 2010 Dec 13.

DOI:10.1016/j.ejrad.2010.11.003

PMID:21146946

Abstract

OBJECTIVE

To measure the mid-sagittal areas of vermis (VA) and of posterior fossa (PFA) and determine their differences among fetuses with various Dandy-Walker (DW) entities and control subjects.

METHODS

We reviewed data in 25 fetal patients with a MR diagnosis of DW complex including hypoplastic vermis (HV), HV with rotation (HVR), and mega cistern magna (MCM), and in 85 fetal controls with normal CNS. PFA and VA of each subject were manually traced on mid-sagittal MR images. Regarding each of VA and PFA, after age correction, we determined statistically significant differences among HVR, HV, MCM, and control groups.

RESULTS

The mean VA residue of MCM was greater than that of the control, which was in turn greater than those of HVR and HV. The mean PF residue of the control was smaller than all other groups.

CONCLUSION

Fetuses with HVR or HV had smaller VA than fetuses with MCM or control subjects. Fetuses with MCM, HVR, or HV had larger PFA than control subjects. These results may be an early step leading to better understanding of the confusion about the PF anomalies in future.

摘要

目的

测量小脑蚓部（VA）和后颅窝（PFA）的中矢状面积，并确定它们在各种 Dandy-Walker （DW）实体和对照受试者中的差异。

方法

我们回顾了 25 例胎儿 MR 诊断为 DW 复合体的患者（包括小脑蚓部发育不全（HV）、旋转性小脑蚓部（HVR）和巨大四脑室（MCM））和 85 例正常中枢神经系统胎儿对照者的数据。手动追踪每个受试者的中矢状面 MR 图像上的 PFA 和 VA。关于 VA 和 PFA 中的每一个，在年龄校正后，我们确定了 HVR、HV、MCM 和对照组之间的统计学显著差异。