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经股静脉栓塞大脑大静脉畸形

Transfemoral venous embolization of vein of Galen malformations.

作者信息

Dowd C F, Halbach V V, Barnwell S L, Higashida R T, Edwards M S, Hieshima G B

机构信息

Department of Radiology, University of California, San Francisco 94143.

出版信息

AJNR Am J Neuroradiol. 1990 Jul-Aug;11(4):643-8.

Abstract

Three infants with vein of Galen malformations, all presenting with congestive heart failure, underwent a total of five embolization procedures that employed a percutaneous transfemoral venous approach to catheterize the vein of Galen. In one instance, direct retrograde catheterization of feeding arterial pedicles to the vein of Galen and embolization of the fistulous connections was achieved via this route. The indications for transfemoral venous treatment included persistent symptoms despite transarterial and transtorcular embolization in one patient, an unsuccessful transarterial embolization attempt (complicated by catheter fracture) in another, and the inadvisability of transarterial embolization because of an excessive number of feeding arteries in a third. Complete obliteration of the malformation was achieved in one patient and significant flow reduction in the other two. Vein of Galen perforation with the catheter tip complicated one procedure. All three patients were stable after clinical follow-ups (9-12 months). The transvenous route to the vein of Galen can be undertaken from a transfemoral approach, obviating surgical exposure of the torcular Herophili. In addition, we introduce the concept of direct retrograde catheterization of the feeding arteries to the vein of Galen malformation by a transfemoral venous approach, a procedure that has not been reported previously.

摘要

三名患有大脑大静脉畸形的婴儿均表现为充血性心力衰竭,总共接受了五次栓塞手术,采用经皮股静脉途径将导管插入大脑大静脉。在其中一例中,通过该途径实现了对大脑大静脉供血动脉蒂的直接逆行插管以及瘘管连接的栓塞。经股静脉治疗的指征包括:一名患者尽管进行了经动脉和经脑室栓塞但仍有持续症状;另一名患者经动脉栓塞尝试失败(并发导管断裂);第三名患者因供血动脉过多而不宜进行经动脉栓塞。一名患者的畸形完全闭塞,另外两名患者的血流显著减少。一次手术因导管尖端导致大脑大静脉穿孔。所有三名患者在临床随访(9 - 12个月)后情况稳定。经股静脉途径可通向大脑大静脉,无需对窦汇进行手术暴露。此外,我们引入了经股静脉途径对大脑大静脉畸形供血动脉进行直接逆行插管的概念,这一手术此前尚未见报道。

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