Department of Radiology and Neuroradiology, Klinikum Duisburg-Sana Kliniken, Zu den Rehwiesen 9, 47055, Duisburg, Germany,
Neuroradiology. 2012 Dec;54(12):1375-9. doi: 10.1007/s00234-012-1059-z. Epub 2012 Jun 29.
Knowledge of venous anatomy and drainage in children with neurovascular diseases is crucial. The primitive marginal sinuses (PMS) are embryonic sinuses forming the later superior sagittal sinus. Their angiographic persistence has not been reported before. The purpose of this study is to demonstrate the angiographic characteristics in children with Vein of Galen malformation and to discuss their embryology and clinical significance.
We retrospectively reviewed digital subtraction angiography and magnetic resonance venography of 102 Vein of Galen malformations (VGM) from the database of two high-load centres for paediatric neurovascular diseases.
We found 10 persistent PMS in 102 children indicating a frequency of 9.8 %. Illustrative cases are shown to demonstrate the vast spectrum of venous variability. The PMS becomes visualised in situations of high-flow arteriovenous shunt in children and can even disappear or remodel after successful shunt reduction or closure.
Knowledge and recognition of the PMS are important for neurointerventionalists in endovascular treatment planning using the transvenous route and can help neurosurgeons in avoiding severe surgical complications.
了解神经血管疾病患儿的静脉解剖结构和引流情况至关重要。原始边缘窦（PMS）是形成后期上矢状窦的胚胎窦。之前尚未报道过其血管造影学上的持续性。本研究旨在展示静脉窦瘤患儿的血管造影特征，并讨论其胚胎学和临床意义。
我们回顾性分析了数据库中来自两个小儿神经血管疾病高负荷中心的 102 例静脉窦瘤（VGM）的数字减影血管造影和磁共振静脉造影。
我们在 102 例患儿中发现了 10 例持续存在的 PMS，表明其发生率为 9.8%。通过典型病例展示了静脉变异的广泛范围。在高流量动静脉分流的情况下，PMS 变得可见，并且在分流减少或关闭成功后，甚至可以消失或重塑。
对于使用经静脉途径进行血管内治疗计划的神经介入医师来说，了解和认识 PMS 非常重要，并且可以帮助神经外科医生避免严重的手术并发症。
