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Biliary Excretion of Cyclosporine in Liver Transplant Patients.

作者信息

Venkataramanan R, Starzl T E, Yang S, Burckart G J, Ptachcinski R J, Shaw B W, Iwatsuki S, Van Thiel D H, Sanghvi A, Seltman H

机构信息

Clinical Pharmacokinetics Laboratorv, School of Pharmacy, Departments of Medicine, Surgery, and Pathology, School of Medicine, University of Pittsburgh.

出版信息

Transplant Proc. 1985 Feb;17(1):286-289.

PMID:21151751
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3000226/
Abstract
摘要

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1
Biliary Excretion of Cyclosporine in Liver Transplant Patients.肝移植患者中环孢素的胆汁排泄
Transplant Proc. 1985 Feb;17(1):286-289.
2
Sirolimus/cyclosporine/tacrolimus interactions on bile flow and biliary excretion of immunosuppressants in a subchronic bile fistula rat model.西罗莫司/环孢素/他克莫司对亚慢性胆瘘大鼠模型胆汁流动及免疫抑制剂胆汁排泄的相互作用
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3
Everolimus/cyclosporine interactions on bile flow and biliary excretion of bile salts and cholesterol in rats.
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4
The effect of P-glycoprotein function inhibition with cyclosporine A on the biodistribution of Tc-99m sestamibi.环孢素A抑制P-糖蛋白功能对锝-99m甲氧基异丁基异腈生物分布的影响。
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5
Influence of cyclosporine on the serum concentration and biliary excretion of mycophenolic acid and 7-O-mycophenolic acid glucuronide.环孢素对霉酚酸及7 - O - 霉酚酸葡萄糖醛酸苷血清浓度和胆汁排泄的影响。
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Effects of curcumin on cyclosporine-induced cholestasis and hypercholesterolemia and on cyclosporine metabolism in the rat.姜黄素对环孢素诱导的大鼠胆汁淤积、高胆固醇血症及环孢素代谢的影响。
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Effect of pharmacological modulation of liver P-glycoproteins on cyclosporin A biliary excretion and cholestasis: a study in isolated perfused rat liver.肝脏P-糖蛋白的药理学调节对环孢素A胆汁排泄及胆汁淤积的影响:离体灌注大鼠肝脏的研究
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Impact of calcineurin inhibitors on urinary excretion of mycophenolic acid and its glucuronide in kidney transplant recipients.钙调神经磷酸酶抑制剂对肾移植受者霉酚酸及其葡萄糖醛酸苷尿排泄的影响。
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Dose-dependent inhibition of transporter-mediated hepatic uptake and biliary excretion of methotrexate by cyclosporine A in an isolated perfused rat liver model.在离体灌流大鼠肝模型中,环孢素 A 呈剂量依赖性抑制甲氨蝶呤的转运体介导的肝摄取和胆汁排泄。
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Biliary secretion of bile acids, lipids, and bilirubin by the transplanted liver. A quantitative study in patients on cyclosporine.
Transplantation. 1991 Dec;52(6):1020-3. doi: 10.1097/00007890-199112000-00016.

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Evaluation of an In Silico PBPK Post-Bariatric Surgery Model through Simulating Oral Drug Bioavailability of Atorvastatin and Cyclosporine.基于计算机的肥胖症手术后 PBPK 模型评估:阿托伐他汀和环孢素口服药物生物利用度的模拟。
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Cyclosporine inhibition of hepatic and intestinal CYP3A4, uptake and efflux transporters: application of PBPK modeling in the assessment of drug-drug interaction potential.环孢菌素抑制肝和肠道 CYP3A4、摄取和外排转运体:PBPK 模型在药物相互作用潜力评估中的应用。
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本文引用的文献

1
A radioimmunoassay to measure cyclosporin A in plasma and serum samples.一种用于测量血浆和血清样本中环孢素A的放射免疫分析方法。
J Immunoassay. 1981;2(1):19-32. doi: 10.1080/01971528108062989.
2
Liquid-chromatographic determination of cyclosporin A in blood and plasma.血液和血浆中环孢素A的液相色谱测定法
Clin Chem. 1981 Aug;27(8):1368-71.
3
Cardiac transplantation with cyclosporin A and prednisone.采用环孢素A和泼尼松进行心脏移植。
Ann Surg. 1982 Sep;196(3):324-9. doi: 10.1097/00000658-198209000-00011.
4
Cardiac transplantation in perspective for the future. Survival, complications, rehabilitation, and cost.心脏移植的未来展望。生存率、并发症、康复及成本。
J Thorac Cardiovasc Surg. 1982 Feb;83(2):168-77.
5
Liver transplantation with use of cyclosporin a and prednisone.使用环孢素A和泼尼松进行肝移植。
N Engl J Med. 1981 Jul 30;305(5):266-9. doi: 10.1056/NEJM198107303050507.
6
The use of cyclosporin A and prednisone in cadaver kidney transplantation.环孢素A和泼尼松在尸体肾移植中的应用。
Surg Gynecol Obstet. 1980 Jul;151(1):17-26.
7
Cyclosporin A initially as the only immunosuppressant in 34 recipients of cadaveric organs: 32 kidneys, 2 pancreases, and 2 livers.环孢素A最初作为唯一的免疫抑制剂应用于34例尸体器官接受者:32例肾移植、2例胰腺移植和2例肝移植。
Lancet. 1979 Nov 17;2(8151):1033-6. doi: 10.1016/s0140-6736(79)92440-1.
8
Biological effects of cyclosporin A: a new antilymphocytic agent.环孢菌素A的生物学效应:一种新型抗淋巴细胞药物。
Agents Actions. 1976 Jul;6(4):468-75. doi: 10.1007/BF01973261.