Sawchuk R J, Cartier L L
Clin Chem. 1981 Aug;27(8):1368-71.
We describe a liquid-chromatographic assay for cyclosporin A in blood and plasma. The method is sensitive enough to allow quantitation of the drug at concentrations observed clinically, is isocratic, required no derivatization, and takes only 10 min of analysis time.
我们描述了一种用于血液和血浆中环孢素A的液相色谱测定法。该方法灵敏度足以对临床观察到的药物浓度进行定量,采用等度洗脱,无需衍生化,且分析时间仅需10分钟。