广泛性发育障碍发病率近期趋势的患病率及解读
Prevalence and interpretation of recent trends in rates of pervasive developmental disorders.
作者信息
Fombonne Eric, Quirke Sara, Hagen Arlene
出版信息
Mcgill J Med. 2009 Nov 16;12(2):73.
Abstract
The aims of this article are to provide an up-to-date review of the methodological features and substantive results of published epidemiological surveys of the prevalence of pervasive developmental disorders (PDD). This article updates previous reviews (1, 2) with the inclusion of new studies made available since then. The specific questions addressed inthis article are: a) how are cases of PDD defined and identified in epidemiological surveys?; b) what are the best estimates for the prevalence of autism and related pervasive developmental disorders considering the methodological implications of the surveys, and c) what interpretation can be given to time trends observed in prevalence rates of PDDs given the hypothesized secular increase in PDDs?
摘要
本文旨在对已发表的广泛性发育障碍（PDD）患病率的流行病学调查的方法学特点和实质性结果进行最新综述。本文纳入了自上次综述（1, 2）以来的新研究，对之前的综述进行了更新。本文探讨的具体问题包括：a）在流行病学调查中，PDD病例是如何定义和识别的？b）考虑到调查的方法学影响，自闭症及相关广泛性发育障碍患病率的最佳估计是多少？c）鉴于假设的PDD长期增加情况，如何解读PDD患病率的时间趋势？
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