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关于人体头部电阻抗谱(EIS)的测量

On the Measurement of Electrical Impedance Spectroscopy (EIS) of the Human Head.

作者信息

Bonmassar Giorgio, Iwaki Sunao, Goldmakher Gregory, Angelone Leonardo M, Belliveau John W, Lev Michael H

机构信息

AA. Martinos Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129 U.S.A.

出版信息

Int J Bioelectromagn. 2010 Jan 1;12(1):32-46.

Abstract

We are introducing a system for Electrical Impedance Spectroscopy (EIS) measurements for future use in Neurological Intensive Care Unit (NICU) settings. The system consists mostly of commercially available components and the software was developed in Labview (National Instruments). The system is based on the principle that acute hemorrhagic stroke may produce detectable changes in the impedance spectrum measured on the subject's scalp due to parenchimal local increases of blood volume. EIS measurements were performed on four healthy control subjects to establish a baseline for a real time stroke detector. Measurements were performed using white noise currents in the 0-50 kHz frequency band using ten shielded electrodes placed on a subject's scalp, with electrical potentials measured with a large-dynamic range for increased EIS accuracy. EIS measurements yielded highly symmetrical impedance spectra, which was only obtainable using the proposed continuos spectral electrical impedance estimation.

摘要

我们正在引入一种用于电阻抗光谱(EIS)测量的系统,以供未来在神经重症监护病房(NICU)环境中使用。该系统主要由商用组件组成,软件是用Labview(美国国家仪器公司)开发的。该系统基于这样的原理:急性出血性中风可能会由于脑实质局部血容量增加而在受试者头皮上测量到的阻抗谱中产生可检测到的变化。对四名健康对照受试者进行了EIS测量,以建立实时中风检测器的基线。测量是在0 - 50 kHz频段使用白噪声电流进行的,使用十个屏蔽电极放置在受试者头皮上,并以大动态范围测量电位以提高EIS精度。EIS测量产生了高度对称的阻抗谱,这只有使用所提出的连续光谱电阻抗估计才能获得。

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