Wang Amy T, Montori Victor M, Murad Mohammad Hassan
Division of General Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Drug News Perspect. 2010 Nov;23(9):607-12. doi: 10.1358/dnp.2010.23.9.1521763.
Fifty years ago, the issue of conflict of interest in biomedical research appeared in the national spotlight and has remained in a state of constant evolution. Government legislation caused a boom in collaborations between physicians, researchers, academic institutions and industry. These relationships continue to advance medical science and make meaningful progress, yet they may threaten the integrity of physicians and researchers and the public's trust in medicine. This article will highlight the evolution of industry relationships and conflict of interest over time, discuss methods by which industry can potentially exert effects and propose new directions for the future.
五十年前，生物医学研究中的利益冲突问题成为全国关注的焦点，并一直处于不断演变的状态。政府立法促使医生、研究人员、学术机构和产业界之间的合作蓬勃发展。这些关系继续推动医学科学进步并取得有意义的进展，但它们可能会威胁到医生和研究人员的诚信以及公众对医学的信任。本文将重点介绍产业界关系和利益冲突随时间的演变，讨论产业界可能施加影响的方式，并为未来提出新的方向。
