Pereira Ana Carolina Figueiredo, Baeta Isabela Guimarães Ribeiro, Costa Júnior Sérgio Rodrigues da, Gontijo Júnior Oswaldo Macedo, Vale Everton Carlos Siviero do
Dermatology Department, Teaching Hospital of the Federal University of Minas Gerais, Brazil.
An Bras Dermatol. 2010 Sep-Oct;85(5):691-4. doi: 10.1590/s0365-05962010000500015.
Elastosis perforans serpiginosa is a rare, primary perforating dermatosis, frequently associated with certain genetic diseases and characterized by the transepidermal extrusion of elastic fibers. The present case report describes this dermatosis in a 19-year old female patient with Down's syndrome, who presented with asymptomatic erythematous, keratotic papules in an arciform pattern, located on her right forearm and knee, which had been present for five years. Following histopathological confirmation, treatment with cryotherapy was initiated, resulting in partial remission of the lesions.
匐行性穿通性弹力纤维病是一种罕见的原发性穿通性皮肤病，常与某些遗传性疾病相关，其特征为弹性纤维经表皮排出。本病例报告描述了一名患有唐氏综合征的19岁女性患者的这种皮肤病，患者右前臂和膝部出现无症状的弧形红斑性角化丘疹，已持续五年。经组织病理学确诊后，开始采用冷冻疗法治疗，皮损部分缓解。
