Wilms A, Dummer R
Dermatologische Klinik, Universitätsspitals Zürich.
Hautarzt. 1997 Dec;48(12):923-5. doi: 10.1007/s001050050687.
Elastosis perforans serpiginosa can arise as a rare complication in patients with Down syndrome. It is one of the primary perforating disorders characterized by transepithelial elimination of abnormal elastic fibers. This may reflect an immunological reaction aquist elastic fibers. We describe a 40-year-old woman with Down's syndrome whose skin lesions were histologically mistaken for lupus vulgaris for a long time.
匐行性穿通性弹力纤维病可作为唐氏综合征患者罕见的并发症出现。它是主要的穿通性疾病之一，其特征是异常弹性纤维经上皮消除。这可能反映了对弹性纤维的免疫反应。我们描述了一名40岁患有唐氏综合征的女性，其皮肤病变在组织学上长期被误诊为寻常狼疮。
