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血压信号解读:休克状态下的生理基础、临床意义和目标。

Interpretation of blood pressure signal: physiological bases, clinical relevance, and objectives during shock states.

机构信息

Laboratoire HIFIH, IFR 132, Université d' Angers et service de réanimation médicale et médecine hyperbare, CHU Angers, Angers Cedex 9, France.

出版信息

Intensive Care Med. 2011 Mar;37(3):411-9. doi: 10.1007/s00134-010-2092-1. Epub 2010 Dec 10.

DOI:10.1007/s00134-010-2092-1
PMID:21153400
Abstract

Achievement of a mean blood pressure (MBP) target is one of the hemodynamic goals to ensure an adequate blood perfusion pressure in critically ill patients. Arterial catheter allows for a continuous and precise monitoring of arterial pressure signal. In addition to giving a precise MBP monitoring, analysis of the blood pressure wave provides information that may help the clinician to interpret hemodynamic status. The interpretation of BP wave requires the understanding of simple principles. In this review, we first discuss the physiological mechanism responsible for arterial pressure generation. We then emphasize the interpretation of the static indexes and the dynamic indexes generated by heart-lung interactions derived from arterial pressure wave. Finally, we focus on MBP value as a therapeutic target in critically ill patients. We discuss the recommended target MBP value by reviewing available data from experimental and clinical studies.

摘要

实现平均血压(MBP)目标是确保危重症患者有足够的血液灌注压力的血流动力学目标之一。动脉导管可连续、精确地监测动脉压信号。除了提供精确的 MBP 监测外,血压波分析还提供了可能有助于临床医生解读血流动力学状态的信息。BP 波的解读需要理解简单的原理。在这篇综述中,我们首先讨论了动脉压产生的生理机制。然后,我们强调了从动脉压波中得出的心肺相互作用产生的静态指标和动态指标的解释。最后,我们关注 MBP 值作为危重症患者的治疗目标。我们通过回顾实验和临床研究中的可用数据来讨论推荐的 MBP 值目标。

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2
Dynamic changes in arterial waveform derived variables and fluid responsiveness in mechanically ventilated patients: a systematic review of the literature.机械通气患者动脉波形衍生变量的动态变化与液体反应性:文献系统综述
Crit Care Med. 2009 Sep;37(9):2642-7. doi: 10.1097/CCM.0b013e3181a590da.
3
Increasing arterial blood pressure with norepinephrine does not improve microcirculatory blood flow: a prospective study.
冠状动脉旁路移植术后平均动脉压的术后波动模式与死亡率。
J Cardiovasc Transl Res. 2024 Apr;17(2):287-297. doi: 10.1007/s12265-023-10475-6. Epub 2024 Jan 9.
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Alpha-Adrenergic Mechanisms in the Cardiovascular Hyperreactivity to Norepinephrine-Infusion in Essential Hypertension.原发性高血压患者对去甲肾上腺素输注引起心血管反应性增强与肾上腺素能机制有关。
Front Endocrinol (Lausanne). 2022 Jul 22;13:824616. doi: 10.3389/fendo.2022.824616. eCollection 2022.
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