Department of Surgery, Ward 6C, Royal Victoria Hospital, Belfast, BT12 6AB, Northern Ireland, UK.
Ir J Med Sci. 2012 Sep;181(3):435-7. doi: 10.1007/s11845-010-0662-4. Epub 2010 Dec 14.
Metastases to the adrenal gland are the second most common type of adrenal mass lesion after adrenocortical adenomas [1, 2]. However, less than 2% of those patients who develop a metachronous metastasis after resection of a primary renal tumour will present with a solitary adrenal tumour [3]. Most of these patients present within several years of the primary diagnosis [4].
A 66-year-old man with a history of left nephrectomy for renal cell carcinoma 18 years previously was investigated for recent weight loss. Computed tomography scanning identified a lesion in the ipsilateral adrenal gland. Hormonal investigations were consistent with a non-functioning mass. Magnetic resonance imaging and positron emission tomography scans suggested a malignant lesion. Laparoscopic adrenalectomy was performed without complication and histopathological examination confirmed metastatic renal cell carcinoma. The patient remains well with no evidence of recurrence at 6 months.
Laparoscopic adrenalectomy is a safe, effective treatment in the treatment of late solitary renal cell cancer metastasis to the ipsilateral adrenal gland.
肾上腺转移瘤是继肾上腺皮质腺瘤之后的第二大常见类型的肾上腺肿块病变[1,2]。然而,在切除原发性肾肿瘤后发生继发转移的患者中,仅有不到 2%会表现为单侧肾上腺肿瘤[3]。这些患者大多在原发性诊断后几年内出现[4]。
一名 66 岁男性,18 年前因左肾细胞癌行左肾切除术,近期出现体重下降。计算机断层扫描(CT)发现同侧肾上腺有一处病变。激素检查结果符合无功能性肿块。磁共振成像(MRI)和正电子发射断层扫描(PET)提示为恶性病变。行腹腔镜肾上腺切除术,无并发症,组织病理学检查证实为转移性肾细胞癌。患者恢复良好,6 个月时无复发迹象。
腹腔镜肾上腺切除术是治疗同侧肾上腺肾细胞癌晚期孤立转移的安全、有效的方法。