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测试丹麦都市传说中酒精可经足部吸收这一说法的有效性:开放性自我实验研究。

Testing the validity of the Danish urban myth that alcohol can be absorbed through feet: open labelled self experimental study.

机构信息

Endocrinology Section, Department of Cardiology and Endocrinology, Hillerød Hospital, Dyrehavevej 29, DK-3400 Hillerød, Denmark.

出版信息

BMJ. 2010 Dec 14;341:c6812. doi: 10.1136/bmj.c6812.

Abstract

OBJECTIVE

To determine the validity of the Danish urban myth that it is possible to get drunk by submerging feet in alcohol.

DESIGN

Open labelled, self experimental study, with no control group.

SETTING

Office of a Danish hospital.

PARTICIPANTS

Three adults, median age 32 (range 31-35), free of chronic skin and liver disease and non-dependent on alcohol and psychoactive drugs.

MAIN OUTCOME MEASURES

The primary end point was the concentration of plasma ethanol (detection limit 2.2 mmol/L (10 mg/100 mL)), measured every 30 minutes for three hours while feet were submerged in a washing-up bowl containing the contents of three 700 mL bottles of vodka. The secondary outcome was self assessment of intoxication related symptoms (self confidence, urge to speak, and number of spontaneous hugs), scored on a scale of 0 to 10.

RESULTS

Plasma ethanol concentrations were below the detection limit of 2.2 mmol/L (10 mg/100 mL) throughout the experiment. No significant changes were observed in the intoxication related symptoms, although self confidence and urge to speak increased slightly at the start of the study, probably due to the setup.

CONCLUSION

Our results suggest that feet are impenetrable to the alcohol component of vodka. We therefore conclude that the Danish urban myth of being able to get drunk by submerging feet in alcoholic beverages is just that; a myth. The implications of the study are many though.

摘要

目的

确定丹麦都市传说“将脚浸入酒精中可致醉酒”是否属实。

设计

无对照组的开放标签、自我实验研究。

地点

丹麦一家医院的办公室。

参与者

3 名成年人,中位年龄 32 岁(范围 31-35 岁),无慢性皮肤和肝脏疾病,不依赖于酒精和精神活性药物。

主要观察指标

主要终点为血浆乙醇浓度(检测限 2.2mmol/L(10mg/100mL)),在将脚浸入装有 3 瓶 700mL 伏特加酒的洗碗盆中时,每 30 分钟测量一次,持续 3 小时。次要观察指标为自我评估的醉酒相关症状(自我信心、说话欲望和自发拥抱次数),评分范围为 0-10 分。

结果

整个实验过程中,血浆乙醇浓度均低于检测限 2.2mmol/L(10mg/100mL)。醉酒相关症状无明显变化,尽管研究开始时自我信心和说话欲望略有增加,可能与实验设置有关。

结论

我们的结果表明,脚对伏特加酒的酒精成分具有不可渗透性。因此,我们得出结论,“将脚浸入酒精饮料中可致醉酒”这一丹麦都市传说只是一个传说。不过,该研究的意义重大。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd41/4787661/0ff197775d9b/hanc818682.f1_default.jpg

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