Arathi Ca, Vijaya C
Department of Pathology, Sree Siddhartha Medical College, Tumkur, India.
J Cytol. 2010 Oct;27(4):140-2. doi: 10.4103/0970-9371.73301.
The low incidence and the non-specific clinical symptoms led us to conclude that the diagnosis of a sebaceous carcinoma of the eyelid often occurs very late. Sebaceous carcinoma of the ocular adnexa is a malignant neoplasm which can exhibit aggressive local behavior, can have pagetoid spread and can metastasize to regional lymph nodes and distant organs. The neoplasm is known to masquerade as other benign and less malignant lesions, and has relatively high morbidity and mortality. Scrape cytology was done in a 70-year-old female with a tumor in left upper lid. Cytological smears were suggestive of sebaceous carcinoma. Subsequently, histopathology confirmed the diagnosis of sebaceous gland carcinoma. The article highlights the role of scrape cytology in early diagnosis and subsequent appropriate surgical management of eyelid sebaceous gland carcinoma, to prevent recurrence and metastasis.
低发病率和非特异性临床症状使我们得出结论，眼睑皮脂腺癌的诊断往往很晚才做出。眼附属器皮脂腺癌是一种恶性肿瘤，可表现出侵袭性的局部行为，可呈派杰样扩散，并可转移至区域淋巴结和远处器官。已知该肿瘤会伪装成其他良性和恶性程度较低的病变，且发病率和死亡率相对较高。对一名左上睑有肿物的70岁女性进行了刮片细胞学检查。细胞学涂片提示为皮脂腺癌。随后，组织病理学证实了皮脂腺癌的诊断。本文强调了刮片细胞学在眼睑皮脂腺癌早期诊断及后续适当手术治疗中的作用，以预防复发和转移。
