Rizvi Syed Ali Raza, Maheshwari Veena
Jawaharlal Nehru Medical College, Aligarh, India.
J Surg Case Rep. 2010 Mar 1;2010(1):5. doi: 10.1093/jscr/2010.1.5.
Sebaceous gland carcinomas (SGC) are highly malignant lid tumors which originate from meibomian glands and rarely from the gland of Zeis, sebaceous gland of caruncle, eyebrows and periocular skin. In many cases correct diagnosis of SGC is delayed because of its ability to masquerade as a variety of other ocular conditions. A forty year old male presented with a left upper eyelid swelling with an ulcerated wound on its nasal aspect. A differential diagnosis of sebaceous gland carcinoma or preseptal cellulitis was made. Contrast enhanced computed tomography showed an ill defined soft tissue density mass in the left orbit encasing the whole of the optic nerve. A total exentration was performed. A diagnosis of meibomian gland carcinoma was confirmed on histopathology. This is a report of an advanced sebaceous gland carcinoma with deep orbital extension. An early diagnosis and appropriate treatment may decrease the long term morbidity and extend the survival rate of such patients.
皮脂腺癌(SGC)是一种高度恶性的眼睑肿瘤,起源于睑板腺,很少起源于蔡司腺、泪阜皮脂腺、眉毛和眼周皮肤。在许多情况下,由于皮脂腺癌能够伪装成多种其他眼部疾病,其正确诊断往往会延迟。一名40岁男性患者,左上眼睑肿胀,鼻侧有溃疡伤口。初步诊断为皮脂腺癌或睑前蜂窝织炎。增强计算机断层扫描显示左眼眶内有一个边界不清的软组织密度肿块,包绕整个视神经。遂进行了全眼球摘除术。组织病理学确诊为睑板腺癌。本文报告一例伴有眼眶深部浸润的晚期皮脂腺癌。早期诊断和适当治疗可能会降低此类患者的长期发病率并延长其生存率。