Carpentier N A, Docquier C E, Pugin P, Lambert P H, Miescher P A
Schweiz Med Wochenschr. 1978 Oct 14;108(41):1601.
Occurrence of immune complexes in infectious mononucleosis has been investigated by the 125I Clq binding assay. Increased serum Clq-binding activity was found in 87% of the 23 patients studied during the acute stage of the disease. The serum Clq-binding material detected has properties identical to those of immune complexes. IgG antibodies dissociated from the complexes at acid pH and F (ab)'2 fragments obtained after treatment by pepsin appeared to be directed against the viral capsid antigen of Epstein-Barr virus.
通过¹²⁵I Clq结合试验对传染性单核细胞增多症中免疫复合物的出现情况进行了研究。在23例处于疾病急性期的患者中，87%的患者血清Clq结合活性升高。检测到的血清Clq结合物质具有与免疫复合物相同的特性。在酸性pH条件下从复合物中解离出的IgG抗体以及经胃蛋白酶处理后获得的F(ab)'₂片段似乎是针对EB病毒的病毒衣壳抗原。
