Department of Women's and Children's Health, Uppsala University, Sweden.
Acta Paediatr. 2011 May;100(5):750-7. doi: 10.1111/j.1651-2227.2010.02122.x. Epub 2011 Jan 12.
Solid tumours constitute 40% of childhood malignancies. The Swedish Childhood Cancer Registry is population based and includes all children with cancer reported from the six paediatric oncology centres in Sweden. The aim was to investigate incidence and survival.
We used the new WHO ICCC-3 for reclassification of the patients. Incidence and survival analyses were performed in the study population.
Two thousand four hundred and eighty-seven children (<15 years) were diagnosed with solid tumours in Sweden between 1983 and 2007. The distribution of diagnoses was similar to that reported in other studies. The annual incidence was 65.3 per million children. The survival rates at 10 years of follow-up have improved significantly when comparing the two time periods, 1983-1995 and 1995-2007 (76 vs. 82%; p < 0.01).
The mean annual incidence of solid tumours in children was 65.3/million and has been stable during the study period. Survival rates for solid tumours at 5, 10 and 20 years follow-up were 80, 79 and 76%, respectively.
固体瘤构成儿童恶性肿瘤的 40%。瑞典儿童癌症登记处是基于人群的，包括来自瑞典六个儿科肿瘤中心报告的所有癌症儿童。目的是调查发病率和生存率。
我们使用新的世卫组织 ICCC-3 对患者进行重新分类。在研究人群中进行了发病率和生存率分析。
1983 年至 2007 年间，瑞典有 2487 名（<15 岁）儿童被诊断患有固体瘤。诊断的分布与其他研究报告的相似。每年的发病率为每百万儿童 65.3 例。与 1983-1995 年和 1995-2007 年两个时期相比，10 年随访的生存率有了显著改善（76%比 82%；p<0.01）。
本研究期间，儿童固体瘤的平均年发病率为 65.3/百万，且保持稳定。5 年、10 年和 20 年随访的固体瘤生存率分别为 80%、79%和 76%。
