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成熟卵巢畸胎瘤对¹⁸F-氟脱氧葡萄糖(FDG)摄取异常强烈:FDG正电子发射断层扫描的一个陷阱。

Unusually intense ¹⁸F-fluorodeoxyglucose (FDG) uptake by a mature ovarian teratoma: a pitfall of FDG positron emission tomography.

作者信息

Miyasaka Naoyuki, Kubota Toshiro

机构信息

Comprehensive Reproductive Medicine, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.

出版信息

J Obstet Gynaecol Res. 2011 Jun;37(6):623-8. doi: 10.1111/j.1447-0756.2010.01393.x. Epub 2010 Dec 15.

Abstract

We present a 32-year-old woman with an ovarian tumor. A large ovarian tumor with solid components was detected by ultrasonography and magnetic resonance imaging. Contrast enhanced magnetic resonance imaging showed strong enhancement within the solid component. ¹⁸F-fluorodeoxyglucose (FDG) positron emission tomography was performed for further evaluation and intense FDG uptake into the solid component was observed with standardized uptake values of 12.8 in the early phase and 14.8 in the delayed phase. Therefore, we could not rule out the possibility of a malignant ovarian tumor, and the patient underwent unilateral salpingo-oophorectomy through laparotomy. The tumor was pathologically diagnosed as a mature teratoma with no malignant elements. Histological examination revealed the solid component to be composed mainly of central nervous tissue, which was most likely to be responsible for the intense FDG uptake.

摘要

我们报告一名32岁患有卵巢肿瘤的女性。超声检查和磁共振成像检测到一个带有实性成分的大型卵巢肿瘤。对比增强磁共振成像显示实性成分内有强烈强化。进行了¹⁸F-氟脱氧葡萄糖(FDG)正电子发射断层扫描以作进一步评估,观察到实性成分有强烈的FDG摄取,早期标准化摄取值为12.8,延迟期为14.8。因此,我们不能排除恶性卵巢肿瘤的可能性,该患者通过剖腹手术接受了单侧输卵管卵巢切除术。肿瘤经病理诊断为成熟畸胎瘤,无恶性成分。组织学检查显示实性成分主要由中枢神经组织构成,这很可能是导致强烈FDG摄取的原因。

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