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卵巢生长性畸胎瘤综合征:一例FDG-PET检查结果的病例报告

Growing teratoma syndrome of the ovary: a case report with FDG-PET findings.

作者信息

Kikawa Satomi, Todo Yukiharu, Minobe Shinichiro, Yamashiro Katsushige, Kato Hidenori, Sakuragi Noriaki

机构信息

Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

出版信息

J Obstet Gynaecol Res. 2011 Jul;37(7):926-32. doi: 10.1111/j.1447-0756.2010.01439.x. Epub 2011 Mar 31.

Abstract

Growing teratoma syndrome (GTS) is defined as enlarging masses during or after chemotherapy for germ cell tumors, and containing only mature teratoma components. A surgical resection is important to confirm a diagnosis and thereby result in the resection of the most appropriate therapeutic management. GTS is a rare event in association with ovarian germ cell tumors. This report presents a case of a 36-year-old female treated surgically for GTS found during the follow-up after chemotherapy and the primary surgical resection of a malignant immature teratoma. Those masses showed fluorodeoxyglucose positron emission tomography positivity and elevated serum CA19-9 prior to the second operation. The histology revealed a mature teratoma. The patient has been disease free for 6 months after the second operation.

摘要

生长性畸胎瘤综合征(GTS)定义为生殖细胞肿瘤化疗期间或化疗后出现的肿块增大,且仅包含成熟畸胎瘤成分。手术切除对于确诊至关重要,从而能够实施最合适的治疗管理。GTS是与卵巢生殖细胞肿瘤相关的罕见情况。本报告介绍了一例36岁女性病例,该患者在化疗及原发性恶性未成熟畸胎瘤手术切除后的随访期间发现GTS并接受了手术治疗。这些肿块在第二次手术前显示氟脱氧葡萄糖正电子发射断层扫描阳性且血清CA19-9升高。组织学检查显示为成熟畸胎瘤。患者在第二次手术后已无病生存6个月。

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