Puig L, Ribera M, Hernanz J M, Belinchón I, Santos-Juanes J, Linares M, Querol I, Colomé E, Caballé G
Servicio de Dermatología, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Actas Dermosifiliogr. 2010 Dec;101(10):827-46.
Scalp lesions are common in psoriasis and difficult to treat. Scientific evidence on the topic is scant and fragmentary, especially with respect to long-term treatment. This consensus statement is based on a critical assessment of the results of a MEDLINE search for clinical trials of the efficacy and safety of therapies used to treat scalp psoriasis. The recommendations were developed by an expert panel using the Delphi process to reach a consensus and then ratified by the members of the Psoriasis Group of the Spanish Academy of Dermatology and Venereology. The recommended induction therapy for scalp psoriasis is either a topical corticosteroid or a topical treatment combining calcipotriol and betamethasone. The choice of an appropriate vehicle is crucial in improving effectiveness and patient adherence to treatment. The only formulations that have been studied in the long-term treatment of scalp psoriasis are a combination of calcipotriol and betamethasone in gel and calcipotriol alone in solution.
头皮病变在银屑病中很常见且难以治疗。关于该主题的科学证据稀少且零碎，尤其是在长期治疗方面。本共识声明基于对MEDLINE搜索用于治疗头皮银屑病的疗法的疗效和安全性的临床试验结果的批判性评估。这些建议由一个专家小组通过德尔菲法达成共识后制定，然后由西班牙皮肤病学和性病学学会银屑病小组的成员批准。推荐的头皮银屑病诱导疗法是外用皮质类固醇或卡泊三醇与倍他米松联合的外用治疗。选择合适的剂型对于提高疗效和患者治疗依从性至关重要。在头皮银屑病长期治疗中研究过的唯一剂型是卡泊三醇与倍他米松的凝胶组合以及单独的卡泊三醇溶液。
