Chan C Stanley, Van Voorhees Abby S, Lebwohl Mark G, Korman Neil J, Young Melodie, Bebo Bruce F, Kalb Robert E, Hsu Sylvia
Department of Dermatology, Baylor College of Medicine, Houston, Texas 77030, USA.
J Am Acad Dermatol. 2009 Jun;60(6):962-71. doi: 10.1016/j.jaad.2008.11.890. Epub 2009 Apr 17.
The scalp is the most commonly affected part of the body in patients with psoriasis. Signs and symptoms of scalp psoriasis vary significantly for individual patients.
A task force of the National Psoriasis Foundation was convened to evaluate treatment options. Our aim was to achieve a consensus for scalp psoriasis therapy.
Reports in the medical literature were reviewed regarding scalp psoriasis therapy.
There is a paucity of evidence-based and double-blind studies in the treatment of scalp psoriasis particularly for long-term therapy. Many of the studies in scalp psoriasis were designed to attain Food and Drug Administration approval for a medication and not to provide treatment guidance.
The recommended short-term or intermittent therapy for scalp psoriasis is topical corticosteroids. The primary alternatives are topical retinoids, vitamin D analogues, and salicylic acid. Combination therapy has many advantages. The choice of an appropriate vehicle is crucial to increase patient compliance. While scalp psoriasis can often be adequately treated with topical therapy, recalcitrant disease may require more aggressive approaches, including systemic agents.
头皮是银屑病患者身体上最常受累的部位。头皮银屑病的体征和症状在个体患者中差异很大。
美国国家银屑病基金会召集了一个特别工作组来评估治疗方案。我们的目标是就头皮银屑病的治疗达成共识。
查阅了医学文献中有关头皮银屑病治疗的报告。
在头皮银屑病治疗方面，尤其是长期治疗，缺乏循证和双盲研究。许多头皮银屑病的研究旨在获得美国食品药品监督管理局对某种药物的批准，而非提供治疗指导。
推荐用于头皮银屑病的短期或间歇性治疗方法是外用糖皮质激素。主要的替代方法是外用维甲酸、维生素D类似物和水杨酸。联合治疗有许多优点。选择合适的剂型对于提高患者依从性至关重要。虽然头皮银屑病通常可用局部治疗充分控制，但顽固性疾病可能需要更积极的方法，包括全身用药。
