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非酮症高血糖性偏侧舞蹈-投掷症。

Hemichorea-hemiballismus in non-ketotic hyperglycaemia.

机构信息

Department of Radiology, Alfred Hospital, Commercial Road, Prahran, Victoria 3181, Australia.

出版信息

J Clin Neurosci. 2011 Feb;18(2):293-4. doi: 10.1016/j.jocn.2010.04.036. Epub 2010 Dec 14.

DOI:10.1016/j.jocn.2010.04.036
PMID:21159513
Abstract

Hemichorea-hemiballismus is a rare complication of nonketotic hyperglycaemia in type 2 diabetes. It is associated with contralateral striatal radiological abnormality, most typically T1 hyperintensity on MRI. We report a case of a 91 year old woman who presented in a nonketotic hyperglycaemic state with right sided hemichorea. Brain CT revealed hyperdensity of the left lentiform nucleus and MRI 15 days post presentation showed left lentiform T1 hyperintensity and enlargement. The chorea improved after control of blood glucose levels. The pathophysiology of this syndrome remains controversial. It is likely that a combination of hyerglycaemia induced basal ganglia metabolic derangement and failure of cerebral blood flow autoregulation contribute to the syndrome.

摘要

偏侧舞动-偏侧投掷症是 2 型糖尿病非酮症高血糖的罕见并发症。它与对侧纹状体的放射学异常有关,最典型的是 MRI 上 T1 高信号。我们报告了一例 91 岁女性,在非酮症高血糖状态下出现右侧偏侧舞动。脑 CT 显示左侧豆状核高密度影,15 天后 MRI 显示左侧豆状核 T1 高信号和增大。血糖控制后舞蹈症改善。该综合征的病理生理学仍存在争议。可能是高血糖诱导的基底节代谢紊乱和脑血流自动调节失败的联合作用导致了该综合征。

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