非酮症高血糖相关性舞蹈症：一例伴有非典型影像学改变的病例报告
Chorea associated with nonketotic hyperglycemia: A case report with atypical imaging changes.
作者信息
Chang Xianchao, Hong Wenke, Yu Hu, Yao Yindan
机构信息
Department of Neurology, Ningbo No.2 Hospital, Ningbo, China.
出版信息
Medicine (Baltimore). 2017 Nov;96(45):e8602. doi: 10.1097/MD.0000000000008602.
INTRODUCTION
This is a unique case of nonketotic hyperglycemic (NKH) chorea in 84-year-old Asian woman. The patient had a history of type 2 diabetes mellitus more than 30 years, but had a poor control of blood sugar. She complained of acute onset of bilateral limb involuntary activities, and being easy to fall within a week. Laboratory testing disclosed hyperglycemia (669 mg/dL), glycated hemoglobin (14%), and normal ketones. The brain computed tomography scan and magnetic resonance imaging did not disclose any abnormality in the basal ganglion unlike most cases. The patient was then diagnosed with NKH chorea. Her symptoms improved quickly.
CONCLUSIONS
NKH chorea with normal imaging may represent a new subtype.
引言
这是一例84岁亚洲女性的非酮症高血糖性（NKH）舞蹈症罕见病例。该患者有30多年2型糖尿病病史，但血糖控制不佳。她主诉双侧肢体突发不自主活动，且在一周内容易跌倒。实验室检查显示血糖升高（669mg/dL）、糖化血红蛋白（14%），酮体正常。与大多数病例不同，脑部计算机断层扫描和磁共振成像未显示基底神经节有任何异常。该患者随后被诊断为NKH舞蹈症。她的症状迅速改善。
结论
影像学正常的NKH舞蹈症可能代表一种新的亚型。
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