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家蚕丝编码基因在果蝇前唾液腺中的特异性表达。

Specific expression of a silk-encoding gene of Bombyx in the anterior salivary gland of Drosophila.

作者信息

Bello B, Couble P

机构信息

Université Claude Bernard-Lyon 1, Centre de Génétique Moléculaire et Cellulaire, UMR 106 du CNRS, Villeurbanne, France.

出版信息

Nature. 1990 Aug 2;346(6283):480-2. doi: 10.1038/346480a0.

DOI:10.1038/346480a0
PMID:2115980
Abstract

Successful expression of genes transferred into distantly related species in which genetic functions have been maintained through evolution has been reported previously. In the case of the silkmoth Bombyx mori and the fruitfly Drosophila melanogaster, both of which produce chorions (eggshells), Bombyx chorion genes are correctly expressed in Drosophila despite their estimated 240-Myr phylogenetic divergence. Here we report that, although Drosophila does not produce silk, mechanisms regulating transcription have been conserved between the salivary gland of the fruitfly and the silk gland of the silkmoth larva.

摘要

先前已有报道称，转入远缘物种的基因能够成功表达，这些物种的基因功能在进化过程中得以保留。在家蚕和果蝇这两种都能产生卵壳的物种中，尽管家蚕的卵壳基因与果蝇的卵壳基因在系统发育上估计有2.4亿年的分歧，但家蚕的卵壳基因在果蝇中仍能正确表达。我们在此报告，尽管果蝇不产丝，但果蝇唾液腺和家蚕幼虫丝腺之间调控转录的机制是保守的。

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Nature. 1990 Aug 2;346(6283):480-2. doi: 10.1038/346480a0.
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