cDNA sequence of a new ras-related gene (rap2b) isolated from human platelets with sequence homology to rap2.
作者信息
Farrell F X, Ohmstede C A, Reep B R, Lapetina E G
机构信息
Division of Cell Biology, Burroughs Wellcome Co., Research Triangle Park, NC 27709.
出版信息
Nucleic Acids Res. 1990 Jul 25;18(14):4281. doi: 10.1093/nar/18.14.4281.
Abstract
摘要
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cDNA sequence of a new ras-related gene (rap2b) isolated from human platelets with sequence homology to rap2.从人血小板中分离出的与rap2具有序列同源性的一种新的ras相关基因（rap2b）的cDNA序列。
Nucleic Acids Res. 1990 Jul 25;18(14):4281. doi: 10.1093/nar/18.14.4281.
2
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Knockdown of Rap2B, a Ras Superfamily Protein, Inhibits Proliferation, Migration, and Invasion in Cervical Cancer Cells via Regulating the ERK1/2 Signaling Pathway.敲低 Ras 超家族蛋白 Rap2B 抑制宫颈癌细胞的增殖、迁移和侵袭并调控 ERK1/2 信号通路。
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本文引用的文献
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Agonist-induced phosphorylation of an immunologically ras-related protein in human erythroleukemia cells.激动剂诱导的人红白血病细胞中一种免疫相关的Ras相关蛋白的磷酸化作用。
Biochem Biophys Res Commun. 1989 Jun 30;161(3):972-8. doi: 10.1016/0006-291x(89)91338-7.
3
A ras-related protein is phosphorylated and translocated by agonists that increase cAMP levels in human platelets.一种与Ras相关的蛋白被能提高人血小板中环磷酸腺苷（cAMP）水平的激动剂磷酸化并使其易位。
Proc Natl Acad Sci U S A. 1989 May;86(9):3131-4. doi: 10.1073/pnas.86.9.3131.
4
ras p21 deletion mutants and monoclonal antibodies as tools for localization of regions relevant to p21 function.ras p21缺失突变体和单克隆抗体作为定位与p21功能相关区域的工具。
Proc Natl Acad Sci U S A. 1986 Aug;83(15):5400-4. doi: 10.1073/pnas.83.15.5400.
5
Thrombolamban, the 22-kDa platelet substrate of cyclic AMP-dependent protein kinase, is immunologically homologous with the Ras family of GTP-binding proteins.受环磷酸腺苷依赖性蛋白激酶作用的22千道尔顿血小板底物——受磷蛋白，与GTP结合蛋白的Ras家族存在免疫同源性。
Proc Natl Acad Sci U S A. 1990 Jan;87(2):758-62. doi: 10.1073/pnas.87.2.758.
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