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脑单光子发射计算机断层扫描在退行性痴呆诊断中有用吗?

Is brain SPECT useful in degenerative dementia diagnosis?

作者信息

Farid Karim, Caillat-Vigneron Nadine, Sibon Igor

机构信息

Department of Nuclear Medicine, Hôtel Dieu Hospital, Paris, France.

出版信息

J Comput Assist Tomogr. 2011 Jan-Feb;35(1):1-3. doi: 10.1097/RCT.0b013e3181f56fda.

DOI:10.1097/RCT.0b013e3181f56fda
PMID:21160432
Abstract

Cerebral blood flow assessment performed by single-photon emission computed tomography (SPECT) of the brain is used to detect early neuronal dysfunction associated with degenerative dementia. Patterns of perfusion abnormalities are different across dementia syndromes. These differences could be used for differential diagnoses and early detection of amnesic mild cognitive impairment in patients with a high risk of conversion to Alzheimer disease. This paper aimed to summarize the expected benefits of single-photon emission computed tomography of the brain in the exploration of degenerative dementias.

摘要

通过脑单光子发射计算机断层扫描(SPECT)进行的脑血流评估用于检测与退行性痴呆相关的早期神经元功能障碍。不同痴呆综合征的灌注异常模式有所不同。这些差异可用于鉴别诊断以及早期检测有转化为阿尔茨海默病高风险患者的遗忘型轻度认知障碍。本文旨在总结脑单光子发射计算机断层扫描在退行性痴呆探索中的预期益处。

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Phys Med Biol. 2021 Jan 27;66(3):035007. doi: 10.1088/1361-6560/abc22e.
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Combining SPECT and Quantitative EEG Analysis for the Automated Differential Diagnosis of Disorders with Amnestic Symptoms.
结合单光子发射计算机断层扫描(SPECT)与定量脑电图分析用于对具有遗忘症状的疾病进行自动鉴别诊断
Front Aging Neurosci. 2017 Sep 7;9:290. doi: 10.3389/fnagi.2017.00290. eCollection 2017.
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Clinical applications of neuroimaging in patients with Alzheimer's disease: a review from the Fourth Canadian Consensus Conference on the Diagnosis and Treatment of Dementia 2012.神经影像学在阿尔茨海默病患者中的临床应用:2012 年第四届加拿大痴呆症诊断和治疗共识会议综述。
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