Farid Karim, Caillat-Vigneron Nadine, Sibon Igor
Department of Nuclear Medicine, Hôtel Dieu Hospital, Paris, France.
J Comput Assist Tomogr. 2011 Jan-Feb;35(1):1-3. doi: 10.1097/RCT.0b013e3181f56fda.
Cerebral blood flow assessment performed by single-photon emission computed tomography (SPECT) of the brain is used to detect early neuronal dysfunction associated with degenerative dementia. Patterns of perfusion abnormalities are different across dementia syndromes. These differences could be used for differential diagnoses and early detection of amnesic mild cognitive impairment in patients with a high risk of conversion to Alzheimer disease. This paper aimed to summarize the expected benefits of single-photon emission computed tomography of the brain in the exploration of degenerative dementias.
通过脑单光子发射计算机断层扫描(SPECT)进行的脑血流评估用于检测与退行性痴呆相关的早期神经元功能障碍。不同痴呆综合征的灌注异常模式有所不同。这些差异可用于鉴别诊断以及早期检测有转化为阿尔茨海默病高风险患者的遗忘型轻度认知障碍。本文旨在总结脑单光子发射计算机断层扫描在退行性痴呆探索中的预期益处。