Chrysant Steven G
Steven G Chrysant, University of Oklahoma and Director of the Oklahoma Cardiovascular and Hypertension Center, Oklahoma City, OK 73132-4904, United States.
World J Cardiol. 2010 Mar 26;2(3):43-9. doi: 10.4330/wjc.v2.i3.43.
The cardiovascular disease continuum (CVDC) is a sequence of events, which begins from a host of cardiovascular risk factors that consists of diabetes mellitus, dyslipidemia, hypertension, smoking and visceral obesity. If it is not intervened with early, it inexorably progresses to atherosclerosis, coronary artery disease, myocardial infarction, left ventricular hypertrophy, and left ventricular dilatation, which lead to left ventricular diastolic or systolic dysfunction and eventually end-stage heart failure and death. Treatment intervention at any stage during its course will either arrest or delay its progress. In this editorial, the cardiovascular risk factors that initiate and perpetuate the CVDC are briefly discussed, with an emphasis on their early prevention or aggressive treatment.
心血管疾病连续体（CVDC）是一系列事件，始于由糖尿病、血脂异常、高血压、吸烟和内脏肥胖组成的众多心血管危险因素。如果不及早干预，它将不可避免地发展为动脉粥样硬化、冠状动脉疾病、心肌梗死、左心室肥厚和左心室扩张，进而导致左心室舒张或收缩功能障碍，最终发展为终末期心力衰竭和死亡。在其病程的任何阶段进行治疗干预都将阻止或延缓其进展。在这篇社论中，将简要讨论引发并使CVDC持续存在的心血管危险因素，重点是它们的早期预防或积极治疗。
