Chrysant S G
Oklahoma Cardiovascular and Hypertension Center, Oklahoma City, Oklahoma, USA.
Hippokratia. 2011 Jan;15(1):7-11.
The cardiovascular disease continuum (CVDC) is a sequence of cardiovascular events, which begins from a cluster of cardiovascular risk factors consisting of diabetes mellitus, dyslipidemia, hypertension, smoking and visceral obesity. If these factors are not intervened with early, they will, inexorably, progress to atherosclerosis, coronary artery disease, myocardial infarction, left ventricular hypertrophy, left ventricular dilatation leading to left ventricular diastolic or systolic dysfunction and eventually end stage heart failure and death. For this concise review, a Medline search of the English language literature between the years 2000 and 2009 was conducted and 33 pertinent publications were selected. Based on the evidence contained in these publications, it is possible that early intervention and treatment of the various cardiovascular risk factors, which initiate and perpetuate the CVDC, could prevent it or arrest its further progress. Therefore, this concise review will emphasize the early detection and treatment of the various cardiovascular risk factors, which initiate and perpetuate the CVDC.
心血管疾病连续体（CVDC）是一系列心血管事件，始于由糖尿病、血脂异常、高血压、吸烟和内脏肥胖组成的心血管危险因素群。如果这些因素不及早干预，它们将不可避免地发展为动脉粥样硬化、冠状动脉疾病、心肌梗死、左心室肥厚、左心室扩张，导致左心室舒张或收缩功能障碍，最终发展为终末期心力衰竭和死亡。为了进行这篇简要综述，我们对2000年至2009年期间的英文文献进行了Medline检索，并选择了33篇相关出版物。基于这些出版物中包含的证据，对启动并使CVDC持续存在的各种心血管危险因素进行早期干预和治疗，有可能预防CVDC或阻止其进一步发展。因此，这篇简要综述将强调对启动并使CVDC持续存在的各种心血管危险因素进行早期检测和治疗。
