Colm O'Morain, Dean of Health Sciences, Trinity College Dublin 2, Ireland.
World J Gastrointest Oncol. 2009 Oct 15;1(1):21-5. doi: 10.4251/wjgo.v1.i1.21.
Colorectal cancer remains a significant cause of morbidity and mortality throughout the world. The incidence of colorectal cancer is nearly four-fold higher in more-developed as compared with less-developed regions of the world. At present an early detection of colorectal cancer remains a crucial step in determining the therapeutic outcomes. Screening programmes have been introduced in an effort to detect colorectal cancer at an early stage or at a precancerous colonic polyp stage. These programmes should be used by the health professionals as an opportunity to educate the public regarding the use of chemoprevention in colorectal cancer, which is the main focus of this review and an attractive concept needing further evaluation.
结直肠癌仍然是全世界发病率和死亡率的主要原因。与世界上欠发达地区相比，结直肠癌的发病率在发达国家高出近四倍。目前，结直肠癌的早期发现仍然是决定治疗效果的关键步骤。筛查计划已经推出，旨在早期发现结直肠癌或癌前结肠息肉阶段。卫生专业人员应利用这些计划，向公众宣传结直肠癌的化学预防，这是本次审查的主要重点，也是一个需要进一步评估的有吸引力的概念。
