Dongil Choi, Hyo K Lim, Hyunchul Rhim, Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50, Ilwon-Dong, Kangnam-Ku, Seoul 135-710, South Korea.
World J Gastrointest Surg. 2010 Apr 27;2(4):137-42. doi: 10.4240/wjgs.v2.i4.137.
Partial hepatectomy has long been the standard treatment modality for patients with hepatocellular carcinoma (HCC), although the majority of patients with HCCs are not candidates for curative resection. Radiofrequency ablation (RFA) has been widely used as the preferred locoregional therapy. RFA and hepatectomy can be complementary to each other for the treatment of multifocal HCCs. Combining hepatectomy with RFA permits the removal of larger tumors while simultaneously ablating any smaller residual tumors. By using this combination treatment, more patients might become candidates for curative resection. For treating recurrent tumors involving the liver after hepatectomy, RFA has been performed recently instead of transcatheter arterial chemoembolization or ethanol ablation. Many retrospective studies on the combination of RFA and hepatectomy demonstrate favorable results of effectiveness and safety. However, further investigation of prospective design will be needed to confirm these encouraging results.
肝切除术一直是肝细胞癌（HCC）患者的标准治疗方式，尽管大多数 HCC 患者不符合根治性切除术的条件。射频消融（RFA）已被广泛用作首选的局部区域治疗方法。RFA 和肝切除术可以相互补充，用于治疗多灶性 HCC。将肝切除术与 RFA 相结合，可以在切除较大肿瘤的同时消融任何较小的残留肿瘤。通过使用这种联合治疗，更多的患者可能成为根治性切除术的候选者。对于治疗肝切除术后肝内复发性肿瘤，最近已经进行了 RFA，而不是经导管动脉化疗栓塞或乙醇消融。许多关于 RFA 和肝切除术联合治疗的回顾性研究显示了有效性和安全性的良好结果。然而，需要进一步进行前瞻性设计的研究来证实这些令人鼓舞的结果。
