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人组织中膜特异性碳酸酐酶(CAIV)的表达。

Membrane specific carbonic anhydrase (CAIV) expression in human tissues.

作者信息

Carter N D, Fryer A, Grant A G, Hume R, Strange R G, Wistrand P J

机构信息

Department of Child Health, St George's Hospital Medical School, London, U.K.

出版信息

Biochim Biophys Acta. 1990 Jul 9;1026(1):113-6. doi: 10.1016/0005-2736(90)90340-t.

Abstract

Membrane-bound carbonic anhydrase IV (CAIV) expression has been evaluated in a range of fetal and adult human tissues and in cell culture. All tissues tested showed expression of CAIV, assessed by Western blotting, with a single immunodetected band at 55 kDa. The levels varied in fetal lung and liver during development and in various zones of the fetal brain. CAIV was clearly expressed in lung, pancreatic tumour and skin cell cultures.

摘要

已在一系列胎儿和成人的人体组织以及细胞培养中评估了膜结合碳酸酐酶IV(CAIV)的表达。通过蛋白质印迹法评估,所有测试组织均显示CAIV表达,在55 kDa处有一条免疫检测条带。在发育过程中,胎儿肺和肝脏以及胎儿大脑的各个区域中,其水平有所不同。CAIV在肺、胰腺肿瘤和皮肤细胞培养物中明显表达。

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