Mao Shan-Ying, Huang Jian-Zheng, Ding Mei-Ping
Department of Neurology, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China.
Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2007 Aug;23(3):324-7.
To investigate the change of latency and interpeak latency of each component of BAEP (brainstem auditory evoked potential, BAEP) and its correlation with PV/PFV (pontine volume/posterior fossa volume, PV/PFV) ratio in OPCA (olivopontocerebellar atrophy, OPCA).
We used Keypoint EMG/EP to determine waves I PL (peak latency, PL), III PL, V PL and I - III IPL (interpeak latency, IPL), III - V IPL, I - V IPL and used 1.5TMR 3D volume rendering software to determine PV (pontine volume, PV), CV(cerebellar volume, CV) and PFV (posterior fossa volume,PFV). Then calculated PV/PFV ratio, CV/PFV ratio and PV/ CV ratio in OPCA group and control group.
Compared with control group, in OPCA group wave IIII PL, I - III IPL were significantly elongated (P < 0.05), III - V IPL was significantly shorten (P < 0.05), PV/PFV ratio was significantly decreased (P < 0.01); there was a positive correlation between III-V IPL and PV/PFV ratio (r = 0.83, P < 0.01).
In patients with OPCA, III PL, I - III IPL of BAEP were elongated and III - V IPL of BAEP was shorten. III - V IPL became shorter when the volume of pontine decreased.
探讨橄榄脑桥小脑萎缩（OPCA）患者脑干听觉诱发电位（BAEP）各波潜伏期及峰间潜伏期的变化及其与脑桥体积/后颅窝体积（PV/PFV）比值的相关性。
采用Keypoint肌电图/诱发电位仪测定波I峰潜伏期（PL）、III PL、V PL及I-III峰间潜伏期（IPL）、III-V IPL、I-V IPL，并使用1.5T磁共振3D容积成像软件测定脑桥体积（PV）、小脑体积（CV）和后颅窝体积（PFV）。然后计算OPCA组和对照组的PV/PFV比值、CV/PFV比值和PV/CV比值。
与对照组相比，OPCA组波III PL、I-III IPL明显延长（P<0.05），III-V IPL明显缩短（P<0.05），PV/PFV比值明显降低（P<0.01）；III-V IPL与PV/PFV比值呈正相关（r=0.83，P<0.01）。
OPCA患者BAEP的III PL、I-III IPL延长，III-V IPL缩短。脑桥体积减小时，III-V IPL变短。
