Department of Applied Life Science, Kon Kuk University, Seoul, 143-701, South Korea.
Immunopharmacol Immunotoxicol. 2011 Sep;33(3):480-3. doi: 10.3109/08923973.2010.539615. Epub 2010 Dec 16.
The stems of Allium victorialis L. var. platyphyllum were extracted and the major essential oil composition and immunotoxicity effects were studied. The analyses were conducted by gas chromatography and mass spectroscopy (GC-MS), which revealed the essential oils of A. victorialis L. var. platyphyllum stems. The A. victorialis L. var. platyphyllum essential oil yield was 1.45%, and GC/MS analysis revealed that its major constituents were allyl methyl disulfide (24.36%), dimethyl trisulfide (11.78%), allyl cis-1-propenyl disulfide (9.17%), allyl methyl trisulfide (4.13%), and dipropyl trisulfide (7.22%). The essential oil had a significant toxic effect against early fourth-stage larvae of Aedes aegypti L. with an LC(50) value of 24.12 ppm and an LC(90) value of 34.67 ppm. Also, allyl methyl disulfide (≥95.0%), dimethyl trisulfide (≥95.0%), allyl cis-1-propenyl disulfide (≥95.0%), allyl methyl trisulfide (≥95.0%), and dipropyl trisulfide (≥95.0%) were tested against the F(21) laboratory strain of A. aegypti. Allyl cis-1-propenyl disulfide (≥95.0%) has good activity with an LC(50) value of 15.35 ppm. Also, the above data indicate that other major compounds may play a more important role in the toxicity of essential oils.
对胜利洋葱的茎进行提取，并研究其主要精油成分和免疫毒性作用。采用气相色谱-质谱联用（GC-MS）分析方法对胜利洋葱宽叶变种的茎进行精油分析，结果表明胜利洋葱宽叶变种茎的精油得率为 1.45%，其主要成分为烯丙基甲基二硫醚（24.36%）、二甲基三硫醚（11.78%）、烯丙基顺-1-丙烯基二硫醚（9.17%）、烯丙基甲基三硫醚（4.13%）和二丙基三硫醚（7.22%）。该精油对埃及伊蚊的四龄早期幼虫具有显著的毒性作用，LC50 值为 24.12ppm，LC90 值为 34.67ppm。此外，烯丙基甲基二硫醚（≥95.0%）、二甲基三硫醚（≥95.0%）、烯丙基顺-1-丙烯基二硫醚（≥95.0%）、烯丙基甲基三硫醚（≥95.0%）和二丙基三硫醚（≥95.0%）被用于测试埃及伊蚊 F21 实验室品系。烯丙基顺-1-丙烯基二硫醚（≥95.0%）具有良好的活性，LC50 值为 15.35ppm。此外，上述数据表明，其他主要化合物可能在精油毒性中发挥更重要的作用。
