Atherton M E, Culp W C, Brown A T, Erdem E
Department of Radiology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA.
Interv Neuroradiol. 2010 Dec;16(4):455-8. doi: 10.1177/159101991001600414. Epub 2010 Dec 17.
A case of cerebral venous thrombosis with intraparenchymal and subarachnoid hemorrhages was initially treated unsuccessfully with mechanical and pharmacologic thrombolysis using intrathrombus tissue plasminogen activator (tPA) and angioplasty, and later successfully treated with an intravascular ultrasound tPA infusion catheter. This new microcatheter allowed direct infusion of tPA while using local therapeutic intravascular ultrasound to increase the thrombolytic effect. Flow was quickly restored. Our patient recovered from coma to discharge home without worsening of existing hemorrhages.
一例伴有脑实质内和蛛网膜下腔出血的脑静脉血栓形成患者，最初采用机械溶栓和使用血栓内组织型纤溶酶原激活剂（tPA）及血管成形术进行药物溶栓治疗，但未成功，后来使用血管内超声tPA输注导管成功治愈。这种新型微导管允许在使用局部治疗性血管内超声增强溶栓效果的同时直接输注tPA。血流迅速恢复。我们的患者从昏迷中苏醒并出院，现有出血情况未恶化。
