Chai Cheng-liang, Lu Qun-ying, Sun Ji-min, Jiang Li-ping, Ling Feng, Zhang Li-juan, Zheng Shou-gui, Zhang Hong, Ge Jun-hua
Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2010 Oct;31(10):1144-7.
To investigate the seroprevalence of tick-borne diseases in humans and domestic animals from rural areas of Zhejiang province.
Anji county, Jindong district and Tiantai county were selected for samples collection according to their geographic locations and historical prevalence of tick-borne diseases. Blood samples of humans and domestic animals were collected in the three sites. An indirect immuno-fluorescent antibody test was used to determine the presence of IgG antibodies of Rickettsiae heilongjiangii, Orientia tsutsugamushi, R. typhi, Anaplasma phagocytosis, Ehrlichia chaffeensis, Bartonella, R. hainan and Coxiella burnetii in these samples.
Six hundred and eighty-three blood samples including 579 from humans and 104 from domestic animals (53 from cattles and 51 from sheep) were collected from the three sites. Antibody positive rates of Orientia tsutsugamushi, R. typhi, Ehrlichia chaffeensis and Coxiella burnetii were significantly different between these sites. IgG from all the 8 pathogens were detected in samples from humans. It was found that the sero-prevalence rates of R. typhi, Bartonella and C. burnetii (20.7%, 10.9%, 5.5%) of adults were higher than those of other Rickettsiae under investigation. The seroprevalence of R. typhi increased along with age. IgG from the 7 pathogens were detected in samples from domestic animals except for Anaplasma phagocytosis. The sero-prevalence rates of R. typhi, Bartonella and R. hainan (69.2%, 51.0%, 22.1%) of adults were higher than those of other Rickettsiae investigated.
Tick-borne diseases did spread widely in humans and domestic animals from different rural areas of Zhejiang province. The sero-prevalence rates of R. typhi, B. henselae, R. hainan and C. burnetii were higher than that from other pathogens.
调查浙江省农村地区人和家畜蜱传疾病的血清流行情况。
根据地理位置和蜱传疾病历史流行情况，选取安吉县、金东区和天台县进行样本采集。在这三个地点采集人和家畜的血液样本。采用间接免疫荧光抗体试验检测这些样本中黑龙江立克次体、恙虫病东方体、伤寒立克次体、嗜吞噬细胞无形体、查菲埃立克体、巴尔通体、海南立克次体和伯纳特柯克斯体的IgG抗体。
从这三个地点共采集了683份血液样本，其中579份来自人，104份来自家畜（53份来自牛，51份来自羊）。恙虫病东方体、伤寒立克次体、查菲埃立克体和伯纳特柯克斯体的抗体阳性率在这些地点之间存在显著差异。在人样本中检测到了所有8种病原体的IgG。发现成人中伤寒立克次体、巴尔通体和伯纳特柯克斯体的血清流行率（20.7%、10.9%、5.5%）高于其他所调查的立克次体。伤寒立克次体的血清流行率随年龄增长而升高。在家畜样本中检测到了除嗜吞噬细胞无形体之外的7种病原体的IgG。成人中伤寒立克次体、巴尔通体和海南立克次体的血清流行率（69.2%、51.0%、22.1%）高于其他所调查的立克次体。
蜱传疾病在浙江省不同农村地区的人和家畜中广泛传播。伤寒立克次体、汉赛巴尔通体、海南立克次体和伯纳特柯克斯体的血清流行率高于其他病原体。
