合成 12-氧代、12-氮杂和 12-硫代胆甾烷三醇。
Synthesis of 12-oxa, 12-aza and 12-thia cholanetriols.
机构信息
Institut des Sciences Moléculaires de Marseille UMR 6263 CNRS, Université d'Aix Marseille III, Faculté des Sciences et Techniques de Saint Jérôme, Marseille, France.
出版信息
Steroids. 2011 Feb;76(3):324-30. doi: 10.1016/j.steroids.2010.12.003. Epub 2010 Dec 14.
Abstract
An efficient synthesis of 12-hetero steroids was achieved via a Baeyer-Villiger oxidation and a photolysis as the key steps. We set out to describe in this paper the first synthesis of 12-aza steroids. The characteristic (1)H and (13)C NMR spectroscopic features of the synthesized compounds are reported.
摘要
通过 Baeyer-Villiger 氧化和光解作为关键步骤，实现了 12-杂类固醇的高效合成。本文首次报道了 12-氮杂类固醇的合成。合成化合物的特征 (1)H 和 (13)C NMR 波谱特征。
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