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粪肠球菌液化亚种拮抗特性的遗传稳定性及一种新型抑菌类细菌素样物质的检测

Genetic stability of the antagonistic character of Enterococcus faecalis ssp. liquefaciens and the detection of a new inhibitory bacteriocin-like substance.

作者信息

Martínez-Bueno M, Gálvez A, Maqueda M, Valdivia E

机构信息

Departamento de Microbiología, Facultad de Ciencias, Universidad de Granada, Spain.

出版信息

Folia Microbiol (Praha). 1990;35(2):113-23. doi: 10.1007/BF02820767.

DOI:10.1007/BF02820767
PMID:2116372
Abstract

The inhibitory capacity of strain S-48 of Enterococcus faecalis ssp. liquefaciens was studied. The strain produces a broad-spectrum peptide antibiotic (AS-48) that has been characterized elsewhere. The isolation of mutants from S-48 after mutagenic treatment revealed another inhibitory substance which remained masked in the wild strain. The protein nature and restricted spectrum of this substance points to its being a bacteriocin.

摘要

研究了粪肠球菌亚种液化亚种S-48菌株的抑制能力。该菌株产生一种广谱肽抗生素(AS-48),其特性已在其他地方进行了描述。诱变处理后从S-48中分离出的突变体揭示了另一种抑制物质,该物质在野生菌株中被掩盖。这种物质的蛋白质性质和有限的谱表明它是一种细菌素。

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Genetic stability of the antagonistic character of Enterococcus faecalis ssp. liquefaciens and the detection of a new inhibitory bacteriocin-like substance.粪肠球菌液化亚种拮抗特性的遗传稳定性及一种新型抑菌类细菌素样物质的检测
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引用本文的文献

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Antilisterial activity of peptide AS-48 and study of changes induced in the cell envelope properties of an AS-48-adapted strain of Listeria monocytogenes.肽AS-48的抗李斯特菌活性及对适应AS-48的单核细胞增生李斯特菌菌株细胞膜特性诱导变化的研究。
Appl Environ Microbiol. 1999 Feb;65(2):618-25. doi: 10.1128/AEM.65.2.618-625.1999.
2
Determination of the gene sequence and the molecular structure of the enterococcal peptide antibiotic AS-48.肠球菌肽抗生素AS-48的基因序列及分子结构测定
J Bacteriol. 1994 Oct;176(20):6334-9. doi: 10.1128/jb.176.20.6334-6339.1994.
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Induction of inhibitory agent produced by Enterococcus faecalis.

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[APPEARANCE AND BEHAVIOR OF SPONTANEOUS MUTANTS OF ENTEROCOCCUS STRAINS WITH RESISTANCE TO ENTEROCIN].[具有抗肠球菌素抗性的肠球菌菌株自发突变体的外观与行为]
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Bactericidal and bacteriolytic action of peptide antibiotic AS-48 against gram-positive and gram-negative bacteria and other organisms.肽抗生素AS-48对革兰氏阳性菌、革兰氏阴性菌及其他生物体的杀菌和溶菌作用。
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