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A transferable plasmid associated with AS-48 production in Enterococcus faecalis.

作者信息

Martínez-Bueno M, Gálvez A, Valdivia E, Maqueda M

机构信息

Departamento de Microbiología, Facultad de Ciencias, Universidad de Granada, Spain.

出版信息

J Bacteriol. 1990 May;172(5):2817-8. doi: 10.1128/jb.172.5.2817-2818.1990.

DOI:10.1128/jb.172.5.2817-2818.1990
PMID:2110152
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC208938/
Abstract

Enterococcus faecalis S-48 produces a peptide antibiotic, AS-48, and a bacteriocin, Bc-48. We have isolated mutants that lack these inhibitory characteristics. Further analysis of the mutants indicates that a plasmid of 56 kilobases (pMB2) may harbor the genes for AS-48. In conjugation experiments, pMB2 has been transferred into a plasmid-free OG1X strain of E. faecalis. The OG1X(pMB2) transconjugant produces the antibiotic AS-48 in solid medium, and the MIC of AS-48 for this strain is the same as that of the donor strain.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/571d/208938/7ea2a3b33e44/jbacter00119-0632-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/571d/208938/7b381cdcee9b/jbacter00119-0631-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/571d/208938/7ea2a3b33e44/jbacter00119-0632-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/571d/208938/7b381cdcee9b/jbacter00119-0631-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/571d/208938/7ea2a3b33e44/jbacter00119-0632-a.jpg

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本文引用的文献

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Simple and rapid method for isolating large plasmid DNA from lactic streptococci.从乳酸链球菌中分离大质粒DNA的简单快速方法。
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Inhibition of Salmonella enterica Cells in Deli-Type Salad by Enterocin AS-48 in Combination with Other Antimicrobials.肠球菌素AS-48与其他抗菌剂联合对熟食类沙拉中肠炎沙门氏菌细胞的抑制作用
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Analysis of the promoters involved in enterocin AS-48 expression.参与肠球菌素AS-48表达的启动子分析。
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Antibacterial activity of some lactic acid bacteria isolated from an Algerian dairy product.从阿尔及利亚乳制品中分离的一些乳酸菌的抗菌活性。
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