医院获得性耐甲氧西林金黄色葡萄球菌肺炎-基于 586 家德国 ICU 网络数据的流行病学和趋势（2005-2009 年）。
Nosocomial methicillin resistant Staphylococcus aureus pneumonia - epidemiology and trends based on data of a network of 586 German ICUs (2005-2009).
机构信息
Institute of Hygiene and Environmental Medicine, Charité University Medicine, Hindenburgdamm 27, 12203 Berlin, Germany.
出版信息
Eur J Med Res. 2010 Nov 30;15(12):514-24. doi: 10.1186/2047-783x-15-12-514.
The epidemiology of MRSA pneumonia varies across countries. One of the most import risk factors for the development of nosocomial MRSA pneumonia is mechanical ventilation. Methicillin resistance in S. aureus ventilator associated pneumonia (VAP) ranged between 37 % in German, 54 % in the US American and 78 % in Asian and Latin American ICUs. In 2009, the incidence density of nosocomial VAP caused by MRSA was 0.28 per 1000 ventilation days in a network of 586 German ICUs. Incidences peaked in neurological and neurosurgical ICUs. Crude hospital mortality in studies performed after 2005 lay between 27 % and 59 % and attributable MRSA pneumonia mortality at 40 %. Since 2005, US American and German data indicate decreasing trends for MRSA pneumonia. Measures to reduce MRSA pneumonia or to control the spread of MRSA include hand hygiene, standard and contact precautions, oral contamination with chlorhexidine, skin decontamination with antiseptics, screening, and (possibly) patient isolation in a single room.
MRSA 肺炎的流行病学在各国之间存在差异。导致医院获得性 MRSA 肺炎的最重要危险因素之一是机械通气。耐甲氧西林金黄色葡萄球菌呼吸机相关性肺炎（VAP）的发生率在德国为 37%，在美国为 54%，在亚洲和拉丁美洲的 ICU 中为 78%。2009 年，在一个由 586 家德国 ICU 组成的网络中，MRSA 引起的医院获得性 VAP 的发病率密度为每 1000 个通气日 0.28 例。发病率在神经科和神经外科 ICU 中达到峰值。2005 年后进行的研究中，粗死亡率在 27%至 59%之间，归因于 MRSA 肺炎的死亡率为 40%。自 2005 年以来，美国和德国的数据表明，MRSA 肺炎呈下降趋势。减少 MRSA 肺炎或控制 MRSA 传播的措施包括手部卫生、标准和接触预防措施、氯己定口腔污染、抗菌剂皮肤消毒、筛查以及（可能）将患者隔离在单人病房中。
Zotero 插件