一氧化氮浓度在慢性疲劳综合征中正常且与活动水平无关：一项病例对照研究。
Nitric oxide concentrations are normal and unrelated to activity level in chronic fatigue syndrome: a case-control study.
机构信息
Division of Musculoskeletal Physiotherapy, Artesis University College (AHA), Department of Health Sciences, Van Aertselaerstraat 31, 2170 Merksem, Belgium.
出版信息
In Vivo. 2010 Nov-Dec;24(6):865-9.
AIM
since patients with chronic fatigue syndrome (CFS) often present elevated levels of nitric oxide (NO) and low levels of physical activity, this study aimed at revealing possible correlations between NO concentration and physical activity.
PATIENTS AND METHODS
thirty CFS patients and 29 age- and gender-matched sedentary controls wore an accelerometer for one week and underwent venous blood sampling at the beginning and the end of the week.
RESULTS
CFS patients were significantly less active (p=0.001), but no significant differences in the amounts of NO (p=0.464 and 0.569) or interaction between NO levels and activity levels in either the CFS patients or controls were revealed.
CONCLUSION
these results provide further evidence for reduced activity levels in CFS patients, but refute there being any interaction between the amount of blood NO and activity level in both groups. The blood NO was neither predictive of, nor dependent on the activity level in CFS.
目的
由于慢性疲劳综合征（CFS）患者的一氧化氮（NO）水平通常升高，而体力活动水平较低，本研究旨在揭示 NO 浓度与体力活动之间可能存在的相关性。
患者和方法
30 名 CFS 患者和 29 名年龄和性别匹配的久坐对照组佩戴加速度计一周，并在一周开始和结束时进行静脉血采样。
结果
CFS 患者的活动量明显较少（p=0.001），但在 CFS 患者和对照组中，NO 量（p=0.464 和 0.569）或 NO 水平与活动水平之间的相互作用均无显著差异。
结论
这些结果进一步证明了 CFS 患者的活动水平降低，但驳斥了两组中血液 NO 量与活动水平之间存在任何相互作用。在 CFS 中，血液 NO 既不是活动水平的预测因素，也不依赖于活动水平。
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