Gershenson Ryan T, Melidone Raffaele, Sutherland-Smith James, Rogers Catherine L
Angell Animal Medical Center Department of Emergency and Critical Care, Boston, MA, USA.
J Am Anim Hosp Assoc. 2011 Jan-Feb;47(1):45-9. doi: 10.5326/JAAHA-MS-5630. Epub 2010 Dec 16.
A 2 yr old spayed female German shepherd presented with a chief complaint of acute onset paraparesis and weight loss. At presentation, the dog was pyrexic, nonambulatory, and had generalized muscle wasting. Neurolocalization was consistent with a thoracolumbar spinal cord lesion. An abdominal ultrasound was performed and revealed a focal dilation (4 cm) of the terminal aorta with evidence of blood stasis consistent with an aortic aneurysm. The dog was euthanized shortly after admission to the hospital and a post mortem examination was performed. Fungal organisms were identified in the aortic aneurysm as well as from the thoracic vertebrae, mesenteric lymph nodes, axillary lymph nodes, spleen, kidneys, liver, lungs, and heart. Although the morphology was consistent with Candida spp., immunohistochemistry and PCR could not definitively identify the causative organism. Mycotic aortic aneurysms are a rare finding in humans and have not been previously reported in the dog. To the authors' knowledge, this is the first known report of an aortic aneurysm associated with systemic fungal infection in a dog.
一只2岁已绝育的雌性德国牧羊犬因急性发作的截瘫和体重减轻为主诉前来就诊。就诊时，该犬发热，不能行走，全身肌肉消瘦。神经定位与胸腰椎脊髓病变一致。进行了腹部超声检查，发现主动脉末端有局灶性扩张（4厘米），并有与主动脉瘤相符的血流淤滞迹象。该犬入院后不久实施了安乐死，并进行了尸检。在主动脉瘤以及胸椎、肠系膜淋巴结、腋窝淋巴结、脾脏、肾脏、肝脏、肺和心脏中均发现了真菌生物体。尽管形态与念珠菌属一致，但免疫组织化学和聚合酶链反应无法明确鉴定出致病生物体。真菌性主动脉瘤在人类中是一种罕见的发现，此前在犬类中尚未有报道。据作者所知，这是犬类中首例已知的与全身性真菌感染相关的主动脉瘤报告。
