Enders Andrew, van der Woerdt Alexandra, Donovan Taryn
Department of Ophthalmology, The Bobst Hospital of the Animal Medical Center, 510 East 62nd Street, New York, NY, 10065, USA.
Department of Pathology, The Bobst Hospital of the Animal Medical Center, 510 East 62nd Street, New York, NY, 10065, USA.
Vet Ophthalmol. 2017 Jan;20(1):84-88. doi: 10.1111/vop.12373. Epub 2016 Mar 3.
This report describes the clinical presentation, diagnosis, histologic lesions, and outcome of endogenous mycotic endophthalmitis secondary to candiduria in a three-year-old female spayed Dachshund. The dog was being treated for Evans syndrome for one month prior to being diagnosed with candiduria and fibrinous uveitis OS. The left eye was enucleated due to secondary glaucoma, and the fungal urinary tract infection was treated successfully. Uveitis developed in the contralateral eye with relapse of the urinary tract infection in the following weeks. The right eye was medically managed until secondary glaucoma developed and was subsequently enucleated. Histopathology of both eyes showed evidence of endophthalmitis with intralesional fungal organisms, consistent with Candida spp. Ocular candidiasis is rare in dogs. To the authors' knowledge, this is the first report of endogenous mycotic endophthalmitis with concurrent candiduria in a dog.
本报告描述了一只三岁已绝育雌性腊肠犬因念珠菌尿继发内源性霉菌性眼内炎的临床表现、诊断、组织学病变及转归。这只狗在被诊断出念珠菌尿和左眼纤维素性葡萄膜炎之前，因伊文氏综合征接受了一个月的治疗。左眼因继发性青光眼而被摘除，真菌性尿路感染得到成功治疗。对侧眼随后发生葡萄膜炎，且在接下来的几周内尿路感染复发。右眼采用药物治疗，直至继发青光眼，随后也被摘除。两只眼睛的组织病理学检查均显示有眼内炎，病变内有真菌生物体，与念珠菌属相符。犬眼部念珠菌病较为罕见。据作者所知，这是首例关于犬内源性霉菌性眼内炎并发念珠菌尿的报告。
