Dental Public Health, Public Health Wales, Mamhilad House, Mamhilad Park Estate, Pontypool, NP4 0YP.
Br Dent J. 2011 Jan 8;210(1):E21. doi: 10.1038/sj.bdj.2010.1179. Epub 2010 Dec 17.
Dental prescribing data in Wales have not been studied in detail previously. The analysis of national data available from Health Solutions Wales showed that dental prescribing in Wales accounted for 9% of total antibacterial prescribing in primary care in 2008. Penicillin and metronidazole constituted the bulk of antibiotics prescribed by dentists. Since the publication of National Institute for Health and Clinical Excellence (NICE) guidance (March 2008) on prophylaxis against infective endocarditis, dental prescriptions for amoxicillin 3g sachets and clindamycin capsules have decreased. Dental prescriptions for fluoride preparations increased in number from 2007 to 2008. Dental prescribing of controlled drugs raises no concern. The figure for antibiotic prescribing in Wales is similar to that of England. Nevertheless, the figure seems a little high, indicating potential inappropriate prescribing behaviour among dentists. Antibiotic resistance is a major public health issue and many patients each year die from infections from bacterial strains that are resistant to one or more antibiotics. Inappropriate use of antibiotics is a major cause of antibiotic resistance and every effort should be made to reduce the number of inappropriate antibiotic prescriptions in dental practice.
威尔士的牙科处方数据以前没有进行过详细研究。从威尔士健康解决方案公司（Health Solutions Wales）提供的全国数据的分析来看，2008 年威尔士的牙科处方占初级保健中所有抗菌药物处方的 9%。青霉素和甲硝唑构成了牙医开具的大部分抗生素。自国家卫生与临床优化研究所（NICE）关于预防感染性心内膜炎的指南（2008 年 3 月）发布以来，用于阿莫西林 3g 小袋和克林霉素胶囊的牙科处方数量有所减少。2007 年至 2008 年，含氟制剂的牙科处方数量有所增加。控制药物的牙科处方没有引起关注。威尔士的抗生素处方数量与英格兰相似。然而，这一数字似乎有点高，表明牙医的处方行为可能存在一些不当之处。抗生素耐药性是一个主要的公共卫生问题，每年都有许多患者因对抗生素具有耐药性的细菌菌株感染而死亡。抗生素的不当使用是抗生素耐药性的主要原因之一，应尽一切努力减少牙科实践中不当的抗生素处方数量。
