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西班牙口腔外科医生治疗牙髓感染时的抗生素处方模式。

Pattern of antibiotic prescription in the management of endodontic infections amongst Spanish oral surgeons.

机构信息

Department of Endodontics, School of Dentistry, University of Seville, Seville, Spain.

出版信息

Int Endod J. 2010 Apr;43(4):342-50. doi: 10.1111/j.1365-2591.2010.01691.x.

DOI:10.1111/j.1365-2591.2010.01691.x
PMID:20487455
Abstract

AIM

To identify antibiotic prescription practices in the treatment of endodontic infections amongst Spanish oral surgeons.

METHODOLOGY

Members of the Spanish Oral Surgery Society (SECIB) were surveyed on antibiotic prescription on six different pulpal and periapical diagnoses. A total of 200 questionnaires were delivered with 127 returned (64%).

RESULTS

The average duration of antibiotic therapy was 7.0 +/- 1.0 days. Ninety five percent of respondents selected amoxicillin as the first choice antibiotic in patients with no medical allergies, alone (34%) or associated to clavulanate (61%). The first drug of choice for patients with an allergy to penicillins was clindamycin 300 mg (65%), followed by azithromycin (15%) and metronidazole-spiramycin (13%). For cases of irreversible pulpitis, 86% of respondents prescribed antibiotics. For the scenario of a necrotic pulp, acute apical periodontitis and no swelling, 71% prescribed antibiotics. Almost 60% of respondents prescribed antibiotics for necrotic pulps with chronic apical periodontitis and a sinus tract; in this clinical situation, odontologists prescribed more frequently antibiotics compared to stomatologists (P = 0.0080; odds ratio = 8.0; C. I. 95% = 1.7-37.1).

CONCLUSIONS

The majority of the members of the SECIB were selecting the appropriate antibiotic for use in endodontic infections, but there are still many who are prescribing antibiotics inappropriately. The use of antibiotics for minor infections, or in some cases in patients without infections, could be a major contributor to the world problem of antimicrobial resistance.

摘要

目的

确定西班牙口腔外科医生治疗牙髓和根尖周感染时的抗生素处方实践。

方法

对西班牙口腔外科学会(SECIB)的成员就六种不同的牙髓和根尖周诊断的抗生素处方进行了调查。共发放了 200 份问卷,收回 127 份(64%)。

结果

抗生素治疗的平均持续时间为 7.0 +/- 1.0 天。95%的受访者选择阿莫西林作为无药物过敏患者的首选抗生素,单独使用(34%)或与克拉维酸联合使用(61%)。对青霉素过敏患者的首选药物是 300mg 克林霉素(65%),其次是阿奇霉素(15%)和甲硝唑-螺旋霉素(13%)。对于不可逆性牙髓炎病例,86%的受访者开了抗生素。对于牙髓坏死、急性根尖周炎且无肿胀的情况,71%的受访者开了抗生素。近 60%的受访者为有慢性根尖周炎和窦道的牙髓坏死开了抗生素;在这种临床情况下,牙医比口腔医生更常开抗生素(P=0.0080;优势比=8.0;95%置信区间=1.7-37.1)。

结论

SECIB 的大多数成员都选择了合适的抗生素用于治疗牙髓感染,但仍有许多人不恰当地开了抗生素。在轻微感染或在某些情况下无感染的患者中使用抗生素,可能是导致世界范围内抗生素耐药问题的一个主要因素。

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