Bernardes Rui, Maduro Cristina, Serranho Pedro, Araújo Adérito, Barbeiro Sílvia, Cunha-Vaz José
Center of New Technologies for Medicine, Association for Innovation and Biomedical Research on Light and Image, Pólo III, Azinhaga Sta. Comba, 3000-548 Coimbra, Portugal.
Opt Express. 2010 Nov 8;18(23):24048-59. doi: 10.1364/OE.18.024048.
Despeckling optical coherence tomograms from the human retina is a fundamental step to a better diagnosis or as a preprocessing stage for retinal layer segmentation. Both of these applications are particularly important in monitoring the progression of retinal disorders. In this study we propose a new formulation for a well-known nonlinear complex diffusion filter. A regularization factor is now made to be dependent on data, and the process itself is now an adaptive one. Experimental results making use of synthetic data show the good performance of the proposed formulation by achieving better quantitative results and increasing computation speed.
去除人眼视网膜光学相干断层扫描图像中的斑点噪声是实现更好诊断的基本步骤,或者作为视网膜层分割的预处理阶段。这两种应用在监测视网膜疾病的进展中都尤为重要。在本研究中,我们为一种著名的非线性复扩散滤波器提出了一种新的公式。现在使正则化因子依赖于数据,并且该过程本身是自适应的。利用合成数据的实验结果表明,所提出的公式通过获得更好的定量结果和提高计算速度而具有良好的性能。